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h16_A2555 h16_A2555 h16_A2554 h16_A2554 lepB lepB h16_A1200 h16_A1200 rpmA rpmA rpsI rpsI rplM rplM prfA prfA rpsO rpsO rpsB rpsB rpmF rpmF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
h16_A2555dsRNA-specific ribonuclease; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (256 aa)    
Predicted Functional Partners:
h16_A2554
GTPase; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
 
  
 0.987
lepB
Signal peptidase I; Belongs to the peptidase S26 family.
  
 0.959
h16_A1200
Predicted metal-dependent phosphoesterase (PHP family).
    
 0.909
rpmA
LSU ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
 
 
 0.905
rpsI
SSU ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
   
 
 0.902
rplM
LSU ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
 
 0.896
prfA
Protein chain release factor A (RF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
  
 
 0.894
rpsO
SSU ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
 
 
 0.893
rpsB
SSU ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
 
 
 0.887
rpmF
LSU ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
  
 
 0.887
Your Current Organism:
Cupriavidus necator
NCBI taxonomy Id: 381666
Other names: Alcaligenes eutropha H16, C. necator H16, Cupriavidus necator ATCC 17699, Cupriavidus necator H16, Ralstonia eutropha ATCC 17699, Ralstonia eutropha H16, Ralstonia eutropha str. H16, Ralstonia eutropha strain H16, Wautersia eutropha H16
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