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pgk pgk LVIS_0661 LVIS_0661 tpiA tpiA eno eno gpmA-2 gpmA-2 gpmA gpmA LVIS_0765 LVIS_0765 pgi pgi LVIS_0660 LVIS_0660 ftsH ftsH LVIS_1420 LVIS_1420
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (400 aa)    
Predicted Functional Partners:
LVIS_0661
Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 0.999
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 0.999
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 
 0.989
gpmA-2
Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
   
 0.966
gpmA
Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
   
 0.965
LVIS_0765
Pyruvate kinase; Belongs to the pyruvate kinase family.
 
 
 0.890
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.828
LVIS_0660
Central glycolytic genes regulator.
  
  
 0.717
ftsH
FtsH-2 peptidase. Metallo peptidase. MEROPS family M41; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
 
  
 0.627
LVIS_1420
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.623
Your Current Organism:
Lactobacillus brevis
NCBI taxonomy Id: 387344
Other names: L. brevis ATCC 367, Lactobacillus brevis ATCC 367, Lactobacillus brevis str. ATCC 367, Lactobacillus brevis strain ATCC 367
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