node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACA70719.1 | ACA71102.1 | PputW619_0213 | PputW619_0597 | PFAM: Aldehyde Dehydrogenase_; KEGG: pen:PSEEN5402 probable aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | PFAM: Aldehyde Dehydrogenase_; KEGG: pen:PSEEN0634 NAD+ dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.906 |
ACA70719.1 | ACA72484.1 | PputW619_0213 | PputW619_1983 | PFAM: Aldehyde Dehydrogenase_; KEGG: pen:PSEEN5402 probable aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.903 |
ACA70719.1 | ACA74895.1 | PputW619_0213 | PputW619_4415 | PFAM: Aldehyde Dehydrogenase_; KEGG: pen:PSEEN5402 probable aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.843 |
ACA70719.1 | acsA | PputW619_0213 | PputW619_0731 | PFAM: Aldehyde Dehydrogenase_; KEGG: pen:PSEEN5402 probable aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.927 |
ACA71102.1 | ACA70719.1 | PputW619_0597 | PputW619_0213 | PFAM: Aldehyde Dehydrogenase_; KEGG: pen:PSEEN0634 NAD+ dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | PFAM: Aldehyde Dehydrogenase_; KEGG: pen:PSEEN5402 probable aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.906 |
ACA71102.1 | ACA72484.1 | PputW619_0597 | PputW619_1983 | PFAM: Aldehyde Dehydrogenase_; KEGG: pen:PSEEN0634 NAD+ dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.903 |
ACA71102.1 | acsA | PputW619_0597 | PputW619_0731 | PFAM: Aldehyde Dehydrogenase_; KEGG: pen:PSEEN0634 NAD+ dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.927 |
ACA72484.1 | ACA70719.1 | PputW619_1983 | PputW619_0213 | Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | PFAM: Aldehyde Dehydrogenase_; KEGG: pen:PSEEN5402 probable aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.903 |
ACA72484.1 | ACA71102.1 | PputW619_1983 | PputW619_0597 | Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | PFAM: Aldehyde Dehydrogenase_; KEGG: pen:PSEEN0634 NAD+ dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.903 |
ACA72484.1 | ACA72485.1 | PputW619_1983 | PputW619_1984 | Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | 0.998 |
ACA72484.1 | ACA72507.1 | PputW619_1983 | PputW619_2007 | Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | 0.993 |
ACA72484.1 | ACA74895.1 | PputW619_1983 | PputW619_4415 | Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.939 |
ACA72484.1 | ACA75086.1 | PputW619_1983 | PputW619_4606 | Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.904 |
ACA72484.1 | acsA | PputW619_1983 | PputW619_0731 | Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.903 |
ACA72484.1 | leuA | PputW619_1983 | PputW619_4199 | Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.963 |
ACA72484.1 | mhpC | PputW619_1983 | PputW619_1981 | Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | Alpha/beta hydrolase fold; Catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6- oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid. | 0.914 |
ACA72484.1 | mhpD | PputW619_1983 | PputW619_1982 | Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 4-oxalocrotonate decarboxylase; Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid. Belongs to the hydratase/decarboxylase family. MhpD subfamily. | 0.971 |
ACA72485.1 | ACA72484.1 | PputW619_1984 | PputW619_1983 | 4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.998 |
ACA72485.1 | ACA72507.1 | PputW619_1984 | PputW619_2007 | 4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | 4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | 0.901 |
ACA72485.1 | mhpC | PputW619_1984 | PputW619_1981 | 4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | Alpha/beta hydrolase fold; Catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6- oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid. | 0.913 |