STRINGSTRING
luxS luxS pfs pfs metE metE Ldb1326 Ldb1326 Ldb0311 Ldb0311 rny rny patC patC cysK2 cysK2 cysK1 cysK1 Ldb1350 Ldb1350 thrB thrB
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
luxSS-ribosylhomocysteinase (Autoinducer-2 production protein LuxS) (AI-2 synthesis protein); Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (159 aa)    
Predicted Functional Partners:
pfs
Nucleoside phosphorylase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
 
 
 0.992
metE
Putative methionine synthase.
    
 0.945
Ldb1326
Conserved hypothetical protein; Putative Cystathionine beta-lyase or Cystathionine gamma-synthase.
  
 
 0.937
Ldb0311
Amino acid permease (fragment).
    
 0.915
rny
Putative phosphohydrolase (HD superfamily); Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family.
     
 0.902
patC
Cystathionine beta-lyase.
    
  0.900
cysK2
Cysteine synthase.
  
 
 0.862
cysK1
Homoserine O-succinyltransferase (fragment); Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.862
Ldb1350
Homoserine dehydrogenase.
    
 0.817
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
     
  0.800
Your Current Organism:
Lactobacillus delbrueckii
NCBI taxonomy Id: 390333
Other names: L. delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002, Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842, Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002, Lactobacillus delbrueckii subsp. bulgaricus DSM 20081
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