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hemA hemA hemC hemC Sare_0428 Sare_0428 Sare_0429 Sare_0429 hemL hemL Sare_0569 Sare_0569 gltX gltX rex rex hemE hemE Sare_3920 Sare_3920 Sare_2699 Sare_2699
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (455 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.999
Sare_0428
Uroporphyrinogen III synthase HEM4; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: stp:Strop_0358 uroporphyrinogen III synthase HEM4.
 
  
 0.995
Sare_0429
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: stp:Strop_0359 porphobilinogen synthase; Belongs to the ALAD family.
 
  
 0.993
hemL
TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: stp:Strop_4100 glutamate-1-semialdehyde-2,1-aminomutase.
 
 0.990
Sare_0569
PFAM: aminotransferase class-III; KEGG: rpd:RPD_2366 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.989
gltX
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
     
 0.965
rex
CoA-binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
       0.923
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.882
Sare_3920
TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: stp:Strop_3545 uroporphyrin-III C-methyltransferase.
 
  
 0.881
Sare_2699
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: stp:Strop_2517 uroporphyrin-III C-methyltransferase.
 
  
 0.860
Your Current Organism:
Salinispora arenicola
NCBI taxonomy Id: 391037
Other names: S. arenicola CNS-205, Salinispora arenicola CNS-205, Salinispora arenicola str. CNS-205, Salinispora arenicola strain CNS-205
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