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bioB bioB bioD bioD Swoo_1865 Swoo_1865 Swoo_1868 Swoo_1868 birA birA Swoo_1867 Swoo_1867 Swoo_1114 Swoo_1114 kbl kbl Swoo_2591 Swoo_2591 thiC thiC Swoo_4123 Swoo_4123
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
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gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (354 aa)    
Predicted Functional Partners:
bioD
Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 
 0.999
Swoo_1865
TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: sse:Ssed_2777 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.982
Swoo_1868
PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: sse:Ssed_2774 biotin biosynthesis protein BioC.
 
  
 0.963
birA
biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
 
 0.958
Swoo_1867
8-amino-7-oxononanoate synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aminotransferase class I and II; aminotransferase class-III; KEGG: sse:Ssed_2775 8-amino-7-oxononanoate synthase.
  
 0.946
Swoo_1114
PFAM: aminotransferase class-III; KEGG: sse:Ssed_1044 beta-alanine--pyruvate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.795
kbl
2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
 
  
 0.705
Swoo_2591
KEGG: sse:Ssed_2014 phosphomethylpyrimidine kinase, thiamine-phosphate diphosphorylase; TIGRFAM: thiamine-phosphate pyrophosphorylase; phosphomethylpyrimidine kinase; PFAM: thiamine monophosphate synthase; Phosphomethylpyrimidine kinase type-1.
 
  
 0.639
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
 
  
 0.620
Swoo_4123
PFAM: biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: sse:Ssed_3967 carbamoyl-phosphate synthase L chain, ATP-binding.
  
 
 0.568
Your Current Organism:
Shewanella woodyi
NCBI taxonomy Id: 392500
Other names: S. woodyi ATCC 51908, Shewanella woodyi ATCC 51908, Shewanella woodyi str. ATCC 51908, Shewanella woodyi strain ATCC 51908
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