STRINGSTRING
pdxA pdxA rsmA rsmA pdxJ pdxJ ABI64848.1 ABI64848.1 ABI65332.1 ABI65332.1 ABI65389.1 ABI65389.1 ABI65516.1 ABI65516.1 ABI66317.1 ABI66317.1 lptD lptD gyrB gyrB ABI65518.1 ABI65518.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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pdxA4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (340 aa)    
Predicted Functional Partners:
rsmA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
 
  
 0.955
pdxJ
Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
 
 
 0.932
ABI64848.1
Aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
     
 0.916
ABI65332.1
PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: bja:bll4777 threonine synthase.
    
  0.901
ABI65389.1
KEGG: xfa:XF2223 threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit.
    
  0.901
ABI65516.1
PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: ccr:CC1688 peptidyl-prolyl cis-trans isomerase family protein.
  
  
 0.872
ABI66317.1
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
   
 0.758
lptD
Organic solvent tolerance protein; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family.
  
    0.741
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
 
      0.709
ABI65518.1
PFAM: permease YjgP/YjgQ family protein; KEGG: ccr:CC1690 hypothetical protein.
       0.611
Your Current Organism:
Maricaulis maris
NCBI taxonomy Id: 394221
Other names: M. maris MCS10, Maricaulis maris MCS10, Maricaulis maris str. MCS10, Maricaulis maris strain MCS10
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