STRINGSTRING
gcvPA gcvPA ABI66500.1 ABI66500.1 gcvH gcvH ABI66503.1 ABI66503.1 glyA glyA ABI65002.1 ABI65002.1 ABI65717.1 ABI65717.1 ABI67094.1 ABI67094.1 ABI66445.1 ABI66445.1 ABI65832.1 ABI65832.1 kbl kbl
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
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gene co-occurrence
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textmining
co-expression
protein homology
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gcvPAGlycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (447 aa)    
Predicted Functional Partners:
ABI66500.1
Glycine dehydrogenase (decarboxylating) beta subunit; PFAM: glycine cleavage system P-protein; KEGG: ccr:CC3352 glycine cleavage system P protein, subunit 2.
 0.999
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 0.999
ABI66503.1
TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); KEGG: pfo:Pfl_4394 glycine cleavage system T protein.
 
 0.999
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
 
 
 0.974
ABI65002.1
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: mlo:mll4470 dihydrolipoamide dehydrogenase.
 
 
 0.923
ABI65717.1
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; FAD dependent oxidoreductase; KEGG: sil:SPO2222 pyruvate dehydrogenase complex, E3 component, lipoamide dehydrogenase, putative.
 
 
 0.922
ABI67094.1
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: ccr:CC0342 2-oxoglutarate dehydrogenase, E3 component, lipoamide dehydrogenase.
 
 
 0.922
ABI66445.1
L-threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: cyb:CYB_0540 putative low specificity L-threonine aldolase.
    
 0.912
ABI65832.1
KEGG: ccr:CC1355 5-aminolevulinic acid synthase; TIGRFAM: 5-aminolevulinic acid synthase; PFAM: aminotransferase, class I and II.
  
 
 0.909
kbl
2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
  
 
 0.909
Your Current Organism:
Maricaulis maris
NCBI taxonomy Id: 394221
Other names: M. maris MCS10, Maricaulis maris MCS10, Maricaulis maris str. MCS10, Maricaulis maris strain MCS10
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