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betB-5 betB-5 betA-4 betA-4 betA-2 betA-2 betI betI betA-3 betA-3 betB-4 betB-4 BAG42601.1 BAG42601.1 putA putA gltS gltS rhf rhf pts-Nag-EIIB pts-Nag-EIIB
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
betB-5Betaine-aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. (489 aa)    
Predicted Functional Partners:
betA-4
Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
 
 
 0.969
betA-2
COG2303: Choline dehydrogenase and related flavoproteins, Ralstonia solanacearum; KEGG, K00108.
  
 
 0.866
betI
TetR/AcrR family transcriptional repressor of bet genes; Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity).
  
  0.854
betA-3
COG2303: Choline dehydrogenase and related flavoproteins, Sinorhizobium meliloti; KEGG, K00108.
  
 
 0.831
betB-4
COG1012: NAD-dependent aldehyde dehydrogenases, Pseudomonas aeruginosa; KEGG, K00130; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.817
BAG42601.1
COG3321: Polyketide synthase modules and related proteins, Sinorhizobium meliloti.
  
 0.760
putA
1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
 
0.736
gltS
COG0069: Glutamate synthase domain 2, Ralstonia solanacearum; KEGG, K00284.
  
 
 0.724
rhf
COG2124: Cytochrome P450, Corynebacterium glutamicum; KEGG, K00517.
  
 
 0.606
pts-Nag-EIIB
COG1263: Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific, Pseudomonas aeruginosa; KEGG, K02803.
     
 0.603
Your Current Organism:
Burkholderia multivorans
NCBI taxonomy Id: 395019
Other names: B. multivorans ATCC 17616, Burkholderia multivorans ATCC 17616, Burkholderia multivorans str. ATCC 17616, Burkholderia multivorans strain ATCC 17616
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