node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
purC | purD | Rleg2_1926 | Rleg2_0535 | KEGG: rec:RHECIAT_CH0002388 phosphoribosylaminoimidazolesuccinocarboxamide synthase protein; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | KEGG: rec:RHECIAT_CH0000977 phosphoribosylamine-glycine ligase protein; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Belongs to the GARS family. | 0.926 |
purC | purE | Rleg2_1926 | Rleg2_3274 | KEGG: rec:RHECIAT_CH0002388 phosphoribosylaminoimidazolesuccinocarboxamide synthase protein; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.996 |
purC | purF | Rleg2_1926 | Rleg2_1042 | KEGG: rec:RHECIAT_CH0002388 phosphoribosylaminoimidazolesuccinocarboxamide synthase protein; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.938 |
purC | purH | Rleg2_1926 | Rleg2_3915 | KEGG: rec:RHECIAT_CH0002388 phosphoribosylaminoimidazolesuccinocarboxamide synthase protein; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | KEGG: rec:RHECIAT_CH0004399 IMP cyclohydrolase/phosphoribosylaminoimidazolecarboxamide formyltransferase protein; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region. | 0.937 |
purC | purK | Rleg2_1926 | Rleg2_3275 | KEGG: rec:RHECIAT_CH0002388 phosphoribosylaminoimidazolesuccinocarboxamide synthase protein; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.944 |
purC | purL | Rleg2_1926 | Rleg2_1934 | KEGG: rec:RHECIAT_CH0002388 phosphoribosylaminoimidazolesuccinocarboxamide synthase protein; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.898 |
purC | purM | Rleg2_1926 | Rleg2_1095 | KEGG: rec:RHECIAT_CH0002388 phosphoribosylaminoimidazolesuccinocarboxamide synthase protein; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | KEGG: rec:RHECIAT_CH0001556 phosphoribosylformylglycinamidine cyclo-ligase protein; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein. | 0.933 |
purC | purN | Rleg2_1926 | Rleg2_1094 | KEGG: rec:RHECIAT_CH0002388 phosphoribosylaminoimidazolesuccinocarboxamide synthase protein; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.922 |
purC | purQ | Rleg2_1926 | Rleg2_1929 | KEGG: rec:RHECIAT_CH0002388 phosphoribosylaminoimidazolesuccinocarboxamide synthase protein; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.960 |
purC | purS | Rleg2_1926 | Rleg2_1927 | KEGG: rec:RHECIAT_CH0002388 phosphoribosylaminoimidazolesuccinocarboxamide synthase protein; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] | 0.965 |
purD | purC | Rleg2_0535 | Rleg2_1926 | KEGG: rec:RHECIAT_CH0000977 phosphoribosylamine-glycine ligase protein; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Belongs to the GARS family. | KEGG: rec:RHECIAT_CH0002388 phosphoribosylaminoimidazolesuccinocarboxamide synthase protein; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | 0.926 |
purD | purE | Rleg2_0535 | Rleg2_3274 | KEGG: rec:RHECIAT_CH0000977 phosphoribosylamine-glycine ligase protein; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Belongs to the GARS family. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.998 |
purD | purF | Rleg2_0535 | Rleg2_1042 | KEGG: rec:RHECIAT_CH0000977 phosphoribosylamine-glycine ligase protein; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Belongs to the GARS family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.998 |
purD | purH | Rleg2_0535 | Rleg2_3915 | KEGG: rec:RHECIAT_CH0000977 phosphoribosylamine-glycine ligase protein; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Belongs to the GARS family. | KEGG: rec:RHECIAT_CH0004399 IMP cyclohydrolase/phosphoribosylaminoimidazolecarboxamide formyltransferase protein; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region. | 0.986 |
purD | purK | Rleg2_0535 | Rleg2_3275 | KEGG: rec:RHECIAT_CH0000977 phosphoribosylamine-glycine ligase protein; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Belongs to the GARS family. | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.968 |
purD | purL | Rleg2_0535 | Rleg2_1934 | KEGG: rec:RHECIAT_CH0000977 phosphoribosylamine-glycine ligase protein; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.969 |
purD | purM | Rleg2_0535 | Rleg2_1095 | KEGG: rec:RHECIAT_CH0000977 phosphoribosylamine-glycine ligase protein; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Belongs to the GARS family. | KEGG: rec:RHECIAT_CH0001556 phosphoribosylformylglycinamidine cyclo-ligase protein; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein. | 0.998 |
purD | purN | Rleg2_0535 | Rleg2_1094 | KEGG: rec:RHECIAT_CH0000977 phosphoribosylamine-glycine ligase protein; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Belongs to the GARS family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.999 |
purD | purQ | Rleg2_0535 | Rleg2_1929 | KEGG: rec:RHECIAT_CH0000977 phosphoribosylamine-glycine ligase protein; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.975 |
purD | purS | Rleg2_0535 | Rleg2_1927 | KEGG: rec:RHECIAT_CH0000977 phosphoribosylamine-glycine ligase protein; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] | 0.943 |