node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACI53889.1 | ACI54862.1 | Rleg2_0592 | Rleg2_1572 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: rec:RHECIAT_CH0001036 molecular chaperone protein DnaJ. | KEGG: rec:RHECIAT_CH0002000 ATP-dependent Clp protease protein, ATP-binding subunit; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | 0.753 |
ACI53889.1 | clpB | Rleg2_0592 | Rleg2_3521 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: rec:RHECIAT_CH0001036 molecular chaperone protein DnaJ. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.783 |
ACI53889.1 | dnaK | Rleg2_0592 | Rleg2_4096 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: rec:RHECIAT_CH0001036 molecular chaperone protein DnaJ. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.984 |
ACI53889.1 | groL | Rleg2_0592 | Rleg2_0470 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: rec:RHECIAT_CH0001036 molecular chaperone protein DnaJ. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.822 |
ACI53889.1 | groS | Rleg2_0592 | Rleg2_0471 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: rec:RHECIAT_CH0001036 molecular chaperone protein DnaJ. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.680 |
ACI53889.1 | grpE | Rleg2_0592 | Rleg2_0008 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: rec:RHECIAT_CH0001036 molecular chaperone protein DnaJ. | Ribulose-phosphate 3-epimerase; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.903 |
ACI53889.1 | hrcA | Rleg2_0592 | Rleg2_0007 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: rec:RHECIAT_CH0001036 molecular chaperone protein DnaJ. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.725 |
ACI54862.1 | ACI53889.1 | Rleg2_1572 | Rleg2_0592 | KEGG: rec:RHECIAT_CH0002000 ATP-dependent Clp protease protein, ATP-binding subunit; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: rec:RHECIAT_CH0001036 molecular chaperone protein DnaJ. | 0.753 |
ACI54862.1 | ACI56859.1 | Rleg2_1572 | Rleg2_3592 | KEGG: rec:RHECIAT_CH0002000 ATP-dependent Clp protease protein, ATP-binding subunit; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | PFAM: heat shock protein DnaJ domain protein; KEGG: rec:RHECIAT_CH0004094 molecular chaperone protein DnaJ. | 0.718 |
ACI54862.1 | dnaJ | Rleg2_1572 | Rleg2_4095 | KEGG: rec:RHECIAT_CH0002000 ATP-dependent Clp protease protein, ATP-binding subunit; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.752 |
ACI54862.1 | dnaK | Rleg2_1572 | Rleg2_4096 | KEGG: rec:RHECIAT_CH0002000 ATP-dependent Clp protease protein, ATP-binding subunit; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.924 |
ACI54862.1 | groL | Rleg2_1572 | Rleg2_0470 | KEGG: rec:RHECIAT_CH0002000 ATP-dependent Clp protease protein, ATP-binding subunit; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.675 |
ACI54862.1 | groS | Rleg2_1572 | Rleg2_0471 | KEGG: rec:RHECIAT_CH0002000 ATP-dependent Clp protease protein, ATP-binding subunit; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.712 |
ACI54862.1 | grpE | Rleg2_1572 | Rleg2_0008 | KEGG: rec:RHECIAT_CH0002000 ATP-dependent Clp protease protein, ATP-binding subunit; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Ribulose-phosphate 3-epimerase; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.825 |
ACI54862.1 | hrcA | Rleg2_1572 | Rleg2_0007 | KEGG: rec:RHECIAT_CH0002000 ATP-dependent Clp protease protein, ATP-binding subunit; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.633 |
ACI55133.1 | dnaK | Rleg2_1848 | Rleg2_4096 | PFAM: nitrogen-fixing NifU domain protein; KEGG: rec:RHECIAT_CH0002288 nitrogen fixation protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.903 |
ACI56859.1 | ACI54862.1 | Rleg2_3592 | Rleg2_1572 | PFAM: heat shock protein DnaJ domain protein; KEGG: rec:RHECIAT_CH0004094 molecular chaperone protein DnaJ. | KEGG: rec:RHECIAT_CH0002000 ATP-dependent Clp protease protein, ATP-binding subunit; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | 0.718 |
ACI56859.1 | clpB | Rleg2_3592 | Rleg2_3521 | PFAM: heat shock protein DnaJ domain protein; KEGG: rec:RHECIAT_CH0004094 molecular chaperone protein DnaJ. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.718 |
ACI56859.1 | dnaK | Rleg2_3592 | Rleg2_4096 | PFAM: heat shock protein DnaJ domain protein; KEGG: rec:RHECIAT_CH0004094 molecular chaperone protein DnaJ. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.941 |
ACI56859.1 | groL | Rleg2_3592 | Rleg2_0470 | PFAM: heat shock protein DnaJ domain protein; KEGG: rec:RHECIAT_CH0004094 molecular chaperone protein DnaJ. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.744 |