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Spea_0374 Spea_0374 cpdA cpdA Spea_0940 Spea_0940 Spea_1019 Spea_1019 Spea_2619 Spea_2619 Spea_2337 Spea_2337 Spea_1182 Spea_1182 Spea_1183 Spea_1183 ndk ndk Spea_3879 Spea_3879 folE folE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Spea_0374PFAM: adenylate cyclase class-I; KEGG: slo:Shew_0319 putative adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. (807 aa)    
Predicted Functional Partners:
cpdA
Calcineurin phosphoesterase domain protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
  
  
 0.976
Spea_0940
TIGRFAM: putative adenylyl cyclase CyaB; PFAM: adenylate cyclase; KEGG: sfr:Sfri_1665 putative adenylyl cyclase CyaB.
  
  
 0.959
Spea_1019
KEGG: sbm:Shew185_1226 putative adenylate/guanylate cyclase.
  
  
 0.946
Spea_2619
KEGG: slo:Shew_2449 anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: formate C-acetyltransferase glycine radical; ATP-cone domain protein.
  
  
  0.918
Spea_2337
KEGG: slo:Shew_2050 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
     
 0.902
Spea_1182
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
 0.900
Spea_1183
TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: shm:Shewmr7_1184 MazG family protein.
     
  0.900
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
  0.900
Spea_3879
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
 0.900
folE
PFAM: GTP cyclohydrolase I; KEGG: slo:Shew_3486 GTP cyclohydrolase I.
  
  
  0.826
Your Current Organism:
Shewanella pealeana
NCBI taxonomy Id: 398579
Other names: S. pealeana ATCC 700345, Shewanella pealeana ATCC 700345, Shewanella pealeana str. ATCC 700345, Shewanella pealeana strain ATCC 700345
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