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nadD nadD Spea_0223 Spea_0223 nadE nadE Spea_0415 Spea_0415 rsfS rsfS nadK nadK cobB cobB Spea_0155 Spea_0155 Spea_1853 Spea_1853 Spea_0651 Spea_0651 Spea_0652 Spea_0652
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
nadDNicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (216 aa)    
Predicted Functional Partners:
Spea_0223
TIGRFAM: competence/damage-inducible protein CinA; PFAM: molybdopterin binding domain; CinA domain protein; KEGG: sbm:Shew185_4098 competence/damage-inducible protein CinA; Belongs to the CinA family.
 
 
 0.974
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
  
 
 0.966
Spea_0415
KEGG: shn:Shewana3_0422 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family.
    
 0.943
rsfS
Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
 
  
 0.941
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.939
cobB
PFAM: Silent information regulator protein Sir2; KEGG: slo:Shew_1662 silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily.
   
 0.922
Spea_0155
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sbm:Shew185_0160 HAD-superfamily hydrolase, subfamily IA, variant 3.
    
 0.916
Spea_1853
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: yen:YE2062 haloacid dehalogenase-like hydrolase family protein.
    
 0.916
Spea_0651
Oxidoreductase; KEGG: slo:Shew_0663 oxidoreductase.
     
 0.905
Spea_0652
PFAM: alanine dehydrogenase/PNT domain protein; KEGG: slo:Shew_0664 alanine dehydrogenase/PNT domain protein.
     
 0.905
Your Current Organism:
Shewanella pealeana
NCBI taxonomy Id: 398579
Other names: S. pealeana ATCC 700345, Shewanella pealeana ATCC 700345, Shewanella pealeana str. ATCC 700345, Shewanella pealeana strain ATCC 700345
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