node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dshi_1160 | folE2 | Dshi_1160 | Dshi_2411 | MazG family protein; Contains 2 MazG domains. | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.800 |
Dshi_1160 | moaA | Dshi_1160 | Dshi_1290 | MazG family protein; Contains 2 MazG domains. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.807 |
Dshi_1160 | ndk | Dshi_1160 | Dshi_1350 | MazG family protein; Contains 2 MazG domains. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.900 |
Dshi_1160 | pykA | Dshi_1160 | Dshi_0228 | MazG family protein; Contains 2 MazG domains. | KEGG: rsp:RSP_1766 pyruvate kinase TIGRFAM: pyruvate kinase PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; high swissprot; Belongs to the pyruvate kinase family. | 0.900 |
Dshi_1160 | relA | Dshi_1160 | Dshi_0194 | MazG family protein; Contains 2 MazG domains. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.934 |
Dshi_1160 | ribA | Dshi_1160 | Dshi_0039 | MazG family protein; Contains 2 MazG domains. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.801 |
Dshi_1160 | ribB | Dshi_1160 | Dshi_2251 | MazG family protein; Contains 2 MazG domains. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.835 |
Dshi_2207 | folE2 | Dshi_2207 | Dshi_2411 | KEGG:sil:SPO0457 hypothetical protein. | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.682 |
Dshi_2399 | Dshi_3102 | Dshi_2399 | Dshi_3102 | Swiss-Prot: Q9X8I0-Dihydroneopterin aldolase folB PFAM: dihydroneopterin aldolase TIGR00525: dihydroneopterin aldolase TIGR00526: FolB domain. | KEGG: rsh:Rsph17029_2670 hypothetical protein. | 0.637 |
Dshi_2399 | folE2 | Dshi_2399 | Dshi_2411 | Swiss-Prot: Q9X8I0-Dihydroneopterin aldolase folB PFAM: dihydroneopterin aldolase TIGR00525: dihydroneopterin aldolase TIGR00526: FolB domain. | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.729 |
Dshi_2399 | ribB | Dshi_2399 | Dshi_2251 | Swiss-Prot: Q9X8I0-Dihydroneopterin aldolase folB PFAM: dihydroneopterin aldolase TIGR00525: dihydroneopterin aldolase TIGR00526: FolB domain. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.517 |
Dshi_3102 | Dshi_2399 | Dshi_3102 | Dshi_2399 | KEGG: rsh:Rsph17029_2670 hypothetical protein. | Swiss-Prot: Q9X8I0-Dihydroneopterin aldolase folB PFAM: dihydroneopterin aldolase TIGR00525: dihydroneopterin aldolase TIGR00526: FolB domain. | 0.637 |
Dshi_3102 | folE2 | Dshi_3102 | Dshi_2411 | KEGG: rsh:Rsph17029_2670 hypothetical protein. | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.645 |
folE2 | Dshi_1160 | Dshi_2411 | Dshi_1160 | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | MazG family protein; Contains 2 MazG domains. | 0.800 |
folE2 | Dshi_2207 | Dshi_2411 | Dshi_2207 | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | KEGG:sil:SPO0457 hypothetical protein. | 0.682 |
folE2 | Dshi_2399 | Dshi_2411 | Dshi_2399 | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | Swiss-Prot: Q9X8I0-Dihydroneopterin aldolase folB PFAM: dihydroneopterin aldolase TIGR00525: dihydroneopterin aldolase TIGR00526: FolB domain. | 0.729 |
folE2 | Dshi_3102 | Dshi_2411 | Dshi_3102 | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | KEGG: rsh:Rsph17029_2670 hypothetical protein. | 0.645 |
folE2 | moaA | Dshi_2411 | Dshi_1290 | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.900 |
folE2 | ndk | Dshi_2411 | Dshi_1350 | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.800 |
folE2 | pykA | Dshi_2411 | Dshi_0228 | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | KEGG: rsp:RSP_1766 pyruvate kinase TIGRFAM: pyruvate kinase PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; high swissprot; Belongs to the pyruvate kinase family. | 0.814 |