node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Plav_0688 | Plav_0691 | Plav_0688 | Plav_0691 | TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: mag:amb0766 glycine cleavage system T protein. | PFAM: glycine cleavage system P-protein; KEGG: rru:Rru_A3048 glycine dehydrogenase (decarboxylating). | 0.999 |
Plav_0688 | Plav_0949 | Plav_0688 | Plav_0949 | TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: mag:amb0766 glycine cleavage system T protein. | PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: mlo:mlr3677 aminomethyltransferase; Belongs to the GcvT family. | 0.933 |
Plav_0688 | Plav_1456 | Plav_0688 | Plav_1456 | TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: mag:amb0766 glycine cleavage system T protein. | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; KEGG: bja:bll0449 dihydrolipoamide dehydrogenase. | 0.959 |
Plav_0688 | Plav_2905 | Plav_0688 | Plav_2905 | TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: mag:amb0766 glycine cleavage system T protein. | TIGRFAM: 5-aminolevulinic acid synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; aminotransferase class-III; KEGG: swi:Swit_3823 5-aminolevulinic acid synthase. | 0.483 |
Plav_0688 | Plav_3138 | Plav_0688 | Plav_3138 | TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: mag:amb0766 glycine cleavage system T protein. | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase; KEGG: acr:Acry_2823 dihydrolipoamide dehydrogenase. | 0.956 |
Plav_0688 | gcvH | Plav_0688 | Plav_0689 | TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: mag:amb0766 glycine cleavage system T protein. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
Plav_0688 | gcvPA | Plav_0688 | Plav_0690 | TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: mag:amb0766 glycine cleavage system T protein. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.999 |
Plav_0688 | glyA | Plav_0688 | Plav_0608 | TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: mag:amb0766 glycine cleavage system T protein. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.994 |
Plav_0688 | glyA-2 | Plav_0688 | Plav_2908 | TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: mag:amb0766 glycine cleavage system T protein. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.994 |
Plav_0691 | Plav_0688 | Plav_0691 | Plav_0688 | PFAM: glycine cleavage system P-protein; KEGG: rru:Rru_A3048 glycine dehydrogenase (decarboxylating). | TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: mag:amb0766 glycine cleavage system T protein. | 0.999 |
Plav_0691 | Plav_0949 | Plav_0691 | Plav_0949 | PFAM: glycine cleavage system P-protein; KEGG: rru:Rru_A3048 glycine dehydrogenase (decarboxylating). | PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: mlo:mlr3677 aminomethyltransferase; Belongs to the GcvT family. | 0.997 |
Plav_0691 | Plav_1456 | Plav_0691 | Plav_1456 | PFAM: glycine cleavage system P-protein; KEGG: rru:Rru_A3048 glycine dehydrogenase (decarboxylating). | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; KEGG: bja:bll0449 dihydrolipoamide dehydrogenase. | 0.932 |
Plav_0691 | Plav_1966 | Plav_0691 | Plav_1966 | PFAM: glycine cleavage system P-protein; KEGG: rru:Rru_A3048 glycine dehydrogenase (decarboxylating). | Threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | 0.916 |
Plav_0691 | Plav_2905 | Plav_0691 | Plav_2905 | PFAM: glycine cleavage system P-protein; KEGG: rru:Rru_A3048 glycine dehydrogenase (decarboxylating). | TIGRFAM: 5-aminolevulinic acid synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; aminotransferase class-III; KEGG: swi:Swit_3823 5-aminolevulinic acid synthase. | 0.916 |
Plav_0691 | Plav_3138 | Plav_0691 | Plav_3138 | PFAM: glycine cleavage system P-protein; KEGG: rru:Rru_A3048 glycine dehydrogenase (decarboxylating). | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase; KEGG: acr:Acry_2823 dihydrolipoamide dehydrogenase. | 0.929 |
Plav_0691 | gcvH | Plav_0691 | Plav_0689 | PFAM: glycine cleavage system P-protein; KEGG: rru:Rru_A3048 glycine dehydrogenase (decarboxylating). | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
Plav_0691 | gcvPA | Plav_0691 | Plav_0690 | PFAM: glycine cleavage system P-protein; KEGG: rru:Rru_A3048 glycine dehydrogenase (decarboxylating). | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.999 |
Plav_0691 | glyA | Plav_0691 | Plav_0608 | PFAM: glycine cleavage system P-protein; KEGG: rru:Rru_A3048 glycine dehydrogenase (decarboxylating). | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.974 |
Plav_0691 | glyA-2 | Plav_0691 | Plav_2908 | PFAM: glycine cleavage system P-protein; KEGG: rru:Rru_A3048 glycine dehydrogenase (decarboxylating). | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.974 |
Plav_0949 | Plav_0688 | Plav_0949 | Plav_0688 | PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: mlo:mlr3677 aminomethyltransferase; Belongs to the GcvT family. | TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: mag:amb0766 glycine cleavage system T protein. | 0.933 |