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kynU kynU kmo kmo tdo2 tdo2 GFO_3168 GFO_3168 nbaC nbaC GFO_0068 GFO_0068 kat kat cpeB cpeB GFO_2721 GFO_2721 GFO_1622 GFO_1622 murQ murQ
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (425 aa)    
Predicted Functional Partners:
kmo
Kynurenine-3-monooxygenase-like protein; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
 
 0.995
tdo2
Tryptophan 2,3-dioxygenase.
 
 
 0.989
GFO_3168
Tryptophan 2,3-dioxygenase.
 
 
 0.989
nbaC
3-hydroxyanthranilic acid dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family.
 
  
  0.977
GFO_0068
N-formylkynurenine (aryl-) formamidase.
 
  
 0.938
kat
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
   
 
 0.903
cpeB
Bifunctional haem catalase-peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
     
  0.900
GFO_2721
O-methyltransferase protein.
  
  
 0.634
GFO_1622
Periplasmic substrate-binding protein.
 
     0.568
murQ
N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate.
   
    0.499
Your Current Organism:
Gramella forsetii
NCBI taxonomy Id: 411154
Other names: Cytophaga sp. KT0803, G. forsetii KT0803, Gramella forsetii KT0803, Gramella forsetii str. KT0803, Gramella forsetii strain KT0803
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