node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACK66263.1 | ACK67685.1 | PCC8801_2238 | PCC8801_3730 | PFAM: aminotransferase class I and II; KEGG: mar:MAE_44340 aspartate aminotransferase. | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: syn:sll1499 ferredoxin-dependent glutamate synthase. | 0.510 |
ACK66263.1 | dapB | PCC8801_2238 | PCC8801_1680 | PFAM: aminotransferase class I and II; KEGG: mar:MAE_44340 aspartate aminotransferase. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | 0.922 |
ACK66263.1 | dapF | PCC8801_2238 | PCC8801_2326 | PFAM: aminotransferase class I and II; KEGG: mar:MAE_44340 aspartate aminotransferase. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.924 |
ACK66263.1 | dapL | PCC8801_2238 | PCC8801_0494 | PFAM: aminotransferase class I and II; KEGG: mar:MAE_44340 aspartate aminotransferase. | Aminotransferase class I and II; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. | 0.901 |
ACK66263.1 | lysA | PCC8801_2238 | PCC8801_0126 | PFAM: aminotransferase class I and II; KEGG: mar:MAE_44340 aspartate aminotransferase. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.468 |
ACK66343.1 | dapF | PCC8801_2327 | PCC8801_2326 | PFAM: S-layer domain protein; KEGG: mar:MAE_31270 S-layer region-like precursor. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.757 |
ACK67685.1 | ACK66263.1 | PCC8801_3730 | PCC8801_2238 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: syn:sll1499 ferredoxin-dependent glutamate synthase. | PFAM: aminotransferase class I and II; KEGG: mar:MAE_44340 aspartate aminotransferase. | 0.510 |
ACK67685.1 | asd | PCC8801_3730 | PCC8801_2926 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: syn:sll1499 ferredoxin-dependent glutamate synthase. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.772 |
ACK67685.1 | carB | PCC8801_3730 | PCC8801_0628 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: syn:sll1499 ferredoxin-dependent glutamate synthase. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: syn:sll0370 carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | 0.766 |
ACK67685.1 | dapB | PCC8801_3730 | PCC8801_1680 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: syn:sll1499 ferredoxin-dependent glutamate synthase. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | 0.424 |
ACK67685.1 | dapF | PCC8801_3730 | PCC8801_2326 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: syn:sll1499 ferredoxin-dependent glutamate synthase. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.686 |
ACK67685.1 | dapL | PCC8801_3730 | PCC8801_0494 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: syn:sll1499 ferredoxin-dependent glutamate synthase. | Aminotransferase class I and II; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. | 0.510 |
ACK67685.1 | murE | PCC8801_3730 | PCC8801_0277 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: syn:sll1499 ferredoxin-dependent glutamate synthase. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.467 |
asd | ACK67685.1 | PCC8801_2926 | PCC8801_3730 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: syn:sll1499 ferredoxin-dependent glutamate synthase. | 0.772 |
asd | dapA | PCC8801_2926 | PCC8801_2927 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.992 |
asd | dapB | PCC8801_2926 | PCC8801_1680 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | 0.846 |
asd | dapF | PCC8801_2926 | PCC8801_2326 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.753 |
asd | lysA | PCC8801_2926 | PCC8801_0126 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.734 |
carB | ACK67685.1 | PCC8801_0628 | PCC8801_3730 | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: syn:sll0370 carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: syn:sll1499 ferredoxin-dependent glutamate synthase. | 0.766 |
carB | dapF | PCC8801_0628 | PCC8801_2326 | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: syn:sll0370 carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.839 |