STRINGSTRING
cobT cobT ABX20789.1 ABX20789.1 cobS cobS cbiA cbiA cbiB cbiB ABX22152.1 ABX22152.1 cobQ cobQ ABX20778.1 ABX20778.1 ABX20774.1 ABX20774.1 ABX20783.1 ABX20783.1 ABX20780.1 ABX20780.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
cobTHypothetical protein; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). Belongs to the CobT family. (354 aa)    
Predicted Functional Partners:
ABX20789.1
Hypothetical protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.
  
 0.999
cobS
Hypothetical protein; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
 
 0.997
cbiA
Hypothetical protein; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
 0.988
cbiB
Hypothetical protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. However, the true cosubstrate could be (R)-1-amino-2-propanol O-2-phosphate, leading to cobinamide phosphate.
 
  
 0.986
ABX22152.1
Hypothetical protein; KEGG: sec:SC0673 7.0e-108 cobC; alpha ribazole-5'-P phosphatase in cobalamin synthesis K02226; COG: COG0406 Fructose-2,6-bisphosphatase; Psort location: Cytoplasmic, score:8.96; Belongs to the phosphoglycerate mutase family.
 
 
 0.982
cobQ
Hypothetical protein; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.966
ABX20778.1
Hypothetical protein; KEGG: stm:STM2029 8.7e-133 cbiF; precorrin-4 C11-methyltransferase K03396; COG: COG2875 Precorrin-4 methylase; Psort location: Cytoplasmic, score:8.96.
 
  
 0.941
ABX20774.1
Hypothetical protein; KEGG: stm:STM2033 2.4e-107 cbiC; precorrin-8X methylmutase K03400; COG: COG2082 Precorrin isomerase; Psort location: Cytoplasmic, score:8.96.
 
  
 0.939
ABX20783.1
Hypothetical protein; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway.
 
  
 0.935
ABX20780.1
Hypothetical protein; KEGG: sec:SC2035 1.0e-122 cbiH; synthesis of vitamin B12 adenosyl cobalamide precursor K03395; COG: COG1010 Precorrin-3B methylase.
 
  
 0.929
Your Current Organism:
Salmonella enterica arizonae
NCBI taxonomy Id: 41514
Other names: S. enterica subsp. arizonae serovar 62:z4,z23:-, Salmonella enterica IIIa 62:z4,z23:-, Salmonella enterica serovar IIIa 62:z4,z23:-, Salmonella enterica subsp. arizonae serovar 62:z4,z23:-
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