node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABX20128.1 | panC | SARI_00181 | SARI_02817 | Hypothetical protein; KEGG: stm:STM2792 3.2e-222 gabT; 4-aminobutyrate aminotransferase K00823:K07250; COG: COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Psort location: Cytoplasmic, score:8.96; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Hypothetical protein; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.913 |
ABX20128.1 | panD | SARI_00181 | SARI_02818 | Hypothetical protein; KEGG: stm:STM2792 3.2e-222 gabT; 4-aminobutyrate aminotransferase K00823:K07250; COG: COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Psort location: Cytoplasmic, score:8.96; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Hypothetical protein; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.915 |
ABX20479.1 | panC | SARI_00553 | SARI_02817 | Hypothetical protein; KEGG: ssn:SSO_2356 4.7e-86 putative regulator; COG: COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.695 |
ABX20479.1 | panD | SARI_00553 | SARI_02818 | Hypothetical protein; KEGG: ssn:SSO_2356 4.7e-86 putative regulator; COG: COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.530 |
ABX22359.1 | ABX23705.1 | SARI_02500 | SARI_03911 | Hypothetical protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Hypothetical protein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.460 |
ABX22359.1 | birA | SARI_02500 | SARI_03524 | Hypothetical protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Hypothetical protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.547 |
ABX22359.1 | panB | SARI_02500 | SARI_02816 | Hypothetical protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Hypothetical protein; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.984 |
ABX22359.1 | panC | SARI_02500 | SARI_02817 | Hypothetical protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Hypothetical protein; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.982 |
ABX22359.1 | panD | SARI_02500 | SARI_02818 | Hypothetical protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Hypothetical protein; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.450 |
ABX22662.1 | birA | SARI_02814 | SARI_03524 | Hypothetical protein; KEGG: stm:STM0183 1.2e-71 folK; 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950; COG: COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | Hypothetical protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.630 |
ABX22662.1 | panB | SARI_02814 | SARI_02816 | Hypothetical protein; KEGG: stm:STM0183 1.2e-71 folK; 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950; COG: COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | Hypothetical protein; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.704 |
ABX22662.1 | panC | SARI_02814 | SARI_02817 | Hypothetical protein; KEGG: stm:STM0183 1.2e-71 folK; 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950; COG: COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | Hypothetical protein; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.641 |
ABX23705.1 | ABX22359.1 | SARI_03911 | SARI_02500 | Hypothetical protein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Hypothetical protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.460 |
ABX23705.1 | birA | SARI_03911 | SARI_03524 | Hypothetical protein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Hypothetical protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.583 |
ABX23705.1 | coaA | SARI_03911 | SARI_03523 | Hypothetical protein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Hypothetical protein; KEGG: sec:SC4027 1.4e-166 coaA; pantothenate kinase K00867; COG: COG1072 Panthothenate kinase. | 0.948 |
ABX23705.1 | panB | SARI_03911 | SARI_02816 | Hypothetical protein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Hypothetical protein; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.501 |
ABX23705.1 | panC | SARI_03911 | SARI_02817 | Hypothetical protein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Hypothetical protein; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.894 |
birA | ABX22359.1 | SARI_03524 | SARI_02500 | Hypothetical protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Hypothetical protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.547 |
birA | ABX22662.1 | SARI_03524 | SARI_02814 | Hypothetical protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Hypothetical protein; KEGG: stm:STM0183 1.2e-71 folK; 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950; COG: COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | 0.630 |
birA | ABX23705.1 | SARI_03524 | SARI_03911 | Hypothetical protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Hypothetical protein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.583 |