node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aceF | gor | APL_0772 | APL_1243 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (E2); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Glutathione reductase. | 0.848 |
aceF | lpdA | APL_0772 | APL_0771 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (E2); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Dihydrolipoyl dehydrogenase. | 0.998 |
aceF | prsA | APL_0772 | APL_0775 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (E2); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.669 |
aceF | sucA | APL_0772 | APL_0455 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (E2); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 2-oxoglutarate dehydrogenase E1 component. | 0.961 |
aceF | sucC | APL_0772 | APL_0452 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (E2); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.927 |
aceF | sucD | APL_0772 | APL_0451 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (E2); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.916 |
gdhA | lpdA | APL_0427 | APL_0771 | NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Dihydrolipoyl dehydrogenase. | 0.850 |
gdhA | sucA | APL_0427 | APL_0455 | NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 2-oxoglutarate dehydrogenase E1 component. | 0.857 |
gdhA | sucC | APL_0427 | APL_0452 | NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.722 |
gor | aceF | APL_1243 | APL_0772 | Glutathione reductase. | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (E2); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.848 |
gor | ppiD | APL_1243 | APL_1003 | Glutathione reductase. | Peptidyl-prolyl cis-trans isomerase D. | 0.860 |
gor | prsA | APL_1243 | APL_0775 | Glutathione reductase. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.653 |
gor | sucA | APL_1243 | APL_0455 | Glutathione reductase. | 2-oxoglutarate dehydrogenase E1 component. | 0.830 |
gor | sucB | APL_1243 | APL_0454 | Glutathione reductase. | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.858 |
lpdA | aceF | APL_0771 | APL_0772 | Dihydrolipoyl dehydrogenase. | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (E2); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.998 |
lpdA | gdhA | APL_0771 | APL_0427 | Dihydrolipoyl dehydrogenase. | NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.850 |
lpdA | ppiD | APL_0771 | APL_1003 | Dihydrolipoyl dehydrogenase. | Peptidyl-prolyl cis-trans isomerase D. | 0.860 |
lpdA | prsA | APL_0771 | APL_0775 | Dihydrolipoyl dehydrogenase. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.715 |
lpdA | sucA | APL_0771 | APL_0455 | Dihydrolipoyl dehydrogenase. | 2-oxoglutarate dehydrogenase E1 component. | 0.989 |
lpdA | sucB | APL_0771 | APL_0454 | Dihydrolipoyl dehydrogenase. | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.996 |