STRINGSTRING
gnd gnd zwf zwf rpiA rpiA rpe rpe rpiB rpiB llmg_2431 llmg_2431 rpe2 rpe2 gntK gntK gntZ gntZ tkt tkt pgiA pgiA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gnd6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (472 aa)    
Predicted Functional Partners:
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
 
 0.997
rpiA
Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
   
 
 0.992
rpe
Ribulose-phosphate 3-epimerase; High confidence in function and specificity; Belongs to the ribulose-phosphate 3-epimerase family.
   
 0.943
rpiB
Ribose 5-phosphate isomerase B; High confidence in function and specificity.
    
 0.942
llmg_2431
Conserved hypothetical protein; 3-carboxymuconate cyclase; Belongs to the cycloisomerase 2 family.
 
  
 0.933
rpe2
Ribulose-phosphate 3-epimerase; High confidence in function and specificity.
   
 0.932
gntK
Gluconate kinase; PF00370: FGGY family of carbohydrate kinases, N-terminal domain, TIGR01314: gntK_FGGY: gluconate kinase; High confidence in function and specificity; Belongs to the FGGY kinase family.
  
 
 0.927
gntZ
GntZ protein; PF03446: NAD binding domain of 6-phosphogluconate dehydrogenase, TIGR00872: gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating); High confidence in function and specificity.
  
  
 
0.912
tkt
Tkt protein; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.894
pgiA
PgiA protein; PF00342: Phosphoglucose isomerase; High confidence in function and specificity; Belongs to the GPI family.
  
  
 0.831
Your Current Organism:
Lactococcus lactis
NCBI taxonomy Id: 416870
Other names: L. lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris str. MG1363, Lactococcus lactis subsp. cremoris strain MG1363
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.