STRINGSTRING
M446_6631 M446_6631 M446_6630 M446_6630 M446_6629 M446_6629 M446_6628 M446_6628 M446_6632 M446_6632 M446_1058 M446_1058 pfp pfp M446_6627 M446_6627 M446_3776 M446_3776 M446_1276 M446_1276 polA polA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
M446_6631PFAM: NUDIX hydrolase; KEGG: mex:Mext_1525 NUDIX hydrolase; Belongs to the Nudix hydrolase family. (169 aa)    
Predicted Functional Partners:
M446_6630
KEGG: mex:Mext_1525 NUDIX hydrolase.
       0.800
M446_6629
PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: mpt:Mpe_A1488 hypothetical protein.
       0.723
M446_6628
PFAM: cytochrome c biogenesis protein transmembrane region; KEGG: mex:Mext_4281 thiol:disulfide interchange protein, putative.
       0.719
M446_6632
Carbonate dehydratase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.
       0.584
M446_1058
KEGG: mex:Mext_0981 hypothetical protein.
  
     0.488
pfp
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
 
     0.450
M446_6627
Hypothetical protein; KEGG: cal:CaO19_4975 hyphally regulated cell wall protein.
       0.446
M446_3776
KEGG: mex:Mext_1204 hypothetical protein.
 
     0.426
M446_1276
KEGG: mex:Mext_1163 hypothetical protein.
  
     0.424
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.406
Your Current Organism:
Methylobacterium sp. 446
NCBI taxonomy Id: 426117
Other names: M. sp. 4-46, Methylobacterium sp. 4-46
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.