STRINGSTRING
hemL hemL ABR65573.1 ABR65573.1 hemA hemA ABR65190.1 ABR65190.1 ABR66286.1 ABR66286.1 ABR66285.1 ABR66285.1 ABR66455.1 ABR66455.1 nadK nadK fbp fbp ABR66284.1 ABR66284.1 ABR65281.1 ABR65281.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
hemLTIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: mmp:MMP0224 glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. (427 aa)    
Predicted Functional Partners:
ABR65573.1
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: mmp:MMP1258 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.995
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.995
ABR65190.1
TIGRFAM: porphobilinogen deaminase; PFAM: Porphobilinogen deaminase; KEGG: mmq:MmarC5_0680 porphobilinogen deaminase.
 
  
 0.947
ABR66286.1
KEGG: mmp:MMP0223 hypothetical protein.
  
    0.891
ABR66285.1
KEGG: mmp:MMP0222 hypothetical protein.
       0.853
ABR66455.1
Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
  
 0.827
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
  
 0.747
fbp
Protein of unknown function DUF100; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
      
 0.732
ABR66284.1
Sodium/proline symporter; TIGRFAM: SSS sodium solute transporter superfamily; sodium/proline symporter; PFAM: Na+? symporter; KEGG: mmp:MMP0221 sodium/proline symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.717
ABR65281.1
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mmp:MMP0966 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
     
 0.713
Your Current Organism:
Methanococcus maripaludis C7
NCBI taxonomy Id: 426368
Other names: M. maripaludis C7, Methanococcus maripaludis str. C7, Methanococcus maripaludis strain C7
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