node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
glyA | ilvE1 | CKL_1284 | CKL_0426 | GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | IlvE1; Predicted threonine dehydratase. | 0.927 |
glyA | sdhB | CKL_1284 | CKL_0700 | GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | SdhB; L-serine dehydratase, beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.959 |
glyA | trpA | CKL_1284 | CKL_1280 | GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | TrpA; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.930 |
glyA | trpB1 | CKL_1284 | CKL_1279 | GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | TrpB1; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.927 |
glyA | trpB2 | CKL_1284 | CKL_3062 | GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | TrpB2; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.904 |
ilvE1 | glyA | CKL_0426 | CKL_1284 | IlvE1; Predicted threonine dehydratase. | GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.927 |
ilvE1 | sdhB | CKL_0426 | CKL_0700 | IlvE1; Predicted threonine dehydratase. | SdhB; L-serine dehydratase, beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.939 |
ilvE1 | trpA | CKL_0426 | CKL_1280 | IlvE1; Predicted threonine dehydratase. | TrpA; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.928 |
ilvE1 | trpB1 | CKL_0426 | CKL_1279 | IlvE1; Predicted threonine dehydratase. | TrpB1; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.948 |
ilvE1 | trpB2 | CKL_0426 | CKL_3062 | IlvE1; Predicted threonine dehydratase. | TrpB2; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.906 |
sdhB | glyA | CKL_0700 | CKL_1284 | SdhB; L-serine dehydratase, beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.959 |
sdhB | ilvE1 | CKL_0700 | CKL_0426 | SdhB; L-serine dehydratase, beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | IlvE1; Predicted threonine dehydratase. | 0.939 |
sdhB | trpA | CKL_0700 | CKL_1280 | SdhB; L-serine dehydratase, beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | TrpA; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.907 |
sdhB | trpB1 | CKL_0700 | CKL_1279 | SdhB; L-serine dehydratase, beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | TrpB1; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |
sdhB | trpB2 | CKL_0700 | CKL_3062 | SdhB; L-serine dehydratase, beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | TrpB2; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |
trpA | glyA | CKL_1280 | CKL_1284 | TrpA; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.930 |
trpA | ilvE1 | CKL_1280 | CKL_0426 | TrpA; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | IlvE1; Predicted threonine dehydratase. | 0.928 |
trpA | sdhB | CKL_1280 | CKL_0700 | TrpA; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | SdhB; L-serine dehydratase, beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.907 |
trpA | trpB1 | CKL_1280 | CKL_1279 | TrpA; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | TrpB1; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.999 |
trpA | trpB2 | CKL_1280 | CKL_3062 | TrpA; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | TrpB2; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.995 |