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recA recA BVU_3423 BVU_3423 polA polA BVU_2638 BVU_2638 BVU_0503 BVU_0503 BVU_0504 BVU_0504 BVU_0862 BVU_0862 BVU_2378 BVU_2378 BVU_2894 BVU_2894 radA radA BVU_3538 BVU_3538
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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recARecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (347 aa)    
Predicted Functional Partners:
BVU_3423
Putative SOS-response transcriptional repressor; Belongs to the peptidase S24 family.
  
 
 0.983
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
 0.980
BVU_2638
ATP-dependent DNA helicase.
  
 0.977
BVU_0503
DNA repair and recombination protein, putative helicase.
  
 0.921
BVU_0504
Putative helicase.
  
 0.921
BVU_0862
Putative regulatory protein; Modulates RecA activity; Belongs to the RecX family.
  
 
 0.917
BVU_2378
Putative bacterioferritin co-migratory protein.
  
  
 0.861
BVU_2894
DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]
  
 0.786
radA
Putative DNA repair protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
   
  
 0.778
BVU_3538
Putative helicase.
 
 
 0.758
Your Current Organism:
Bacteroides vulgatus
NCBI taxonomy Id: 435590
Other names: B. vulgatus ATCC 8482, Bacteroides vulgatus ATCC 8482, Bacteroides vulgatus str. ATCC 8482, Bacteroides vulgatus strain ATCC 8482
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