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dapF dapF dapL dapL murE murE BDI_3837 BDI_3837 lysA lysA BDI_1378 BDI_1378 BDI_3565 BDI_3565 asd asd BDI_0326 BDI_0326 BDI_0580 BDI_0580 BDI_3425 BDI_3425
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (269 aa)    
Predicted Functional Partners:
dapL
Aspartate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate.
 
 0.982
murE
Probable UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
 
  
 0.936
BDI_3837
Diaminopimelate decarboxylase.
 
 0.936
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
 
 0.934
BDI_1378
Putative aminotransferase.
  
 0.921
BDI_3565
Putative oxidoreductase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate.
    
 0.903
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
  
 0.762
BDI_0326
Glutamate synthase, large subunit.
  
  
 0.701
BDI_0580
Carbamyl phosphate synthetase.
    
 0.655
BDI_3425
Glutamine-dependent carbamyl phosphate synthetase.
    
 0.598
Your Current Organism:
Parabacteroides distasonis
NCBI taxonomy Id: 435591
Other names: P. distasonis ATCC 8503, Parabacteroides distasonis ATCC 8503, Parabacteroides distasonis str. ATCC 8503, Parabacteroides distasonis strain ATCC 8503
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