node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BDI_1107 | BDI_2337 | BDI_1107 | BDI_2337 | Phosphoserine phosphatase. | L-threonine-O-3-phosphate decarboxylase, putative. | 0.494 |
BDI_1107 | hisA | BDI_1107 | BDI_2017 | Phosphoserine phosphatase. | Imidazole-4-carboxamide isomerase. | 0.729 |
BDI_1107 | hisB | BDI_1107 | BDI_0969 | Phosphoserine phosphatase. | Histidine biosynthesis bifunctional protein hisB; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | 0.830 |
BDI_1107 | hisC | BDI_1107 | BDI_0968 | Phosphoserine phosphatase. | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.494 |
BDI_1107 | hisD | BDI_1107 | BDI_0967 | Phosphoserine phosphatase. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.667 |
BDI_1107 | hisF | BDI_1107 | BDI_2018 | Phosphoserine phosphatase. | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.799 |
BDI_1107 | hisG | BDI_1107 | BDI_0966 | Phosphoserine phosphatase. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. | 0.495 |
BDI_1107 | hisH | BDI_1107 | BDI_2016 | Phosphoserine phosphatase. | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.735 |
BDI_1107 | hisI | BDI_1107 | BDI_2019 | Phosphoserine phosphatase. | phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase; In the N-terminal section; belongs to the PRA-CH family. | 0.961 |
BDI_2020 | hisA | BDI_2020 | BDI_2017 | Putative ATP-binding protein involved in cell division. | Imidazole-4-carboxamide isomerase. | 0.709 |
BDI_2020 | hisF | BDI_2020 | BDI_2018 | Putative ATP-binding protein involved in cell division. | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.752 |
BDI_2020 | hisH | BDI_2020 | BDI_2016 | Putative ATP-binding protein involved in cell division. | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.709 |
BDI_2020 | hisI | BDI_2020 | BDI_2019 | Putative ATP-binding protein involved in cell division. | phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase; In the N-terminal section; belongs to the PRA-CH family. | 0.818 |
BDI_2337 | BDI_1107 | BDI_2337 | BDI_1107 | L-threonine-O-3-phosphate decarboxylase, putative. | Phosphoserine phosphatase. | 0.494 |
BDI_2337 | hisA | BDI_2337 | BDI_2017 | L-threonine-O-3-phosphate decarboxylase, putative. | Imidazole-4-carboxamide isomerase. | 0.761 |
BDI_2337 | hisB | BDI_2337 | BDI_0969 | L-threonine-O-3-phosphate decarboxylase, putative. | Histidine biosynthesis bifunctional protein hisB; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | 0.956 |
BDI_2337 | hisD | BDI_2337 | BDI_0967 | L-threonine-O-3-phosphate decarboxylase, putative. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.836 |
BDI_2337 | hisF | BDI_2337 | BDI_2018 | L-threonine-O-3-phosphate decarboxylase, putative. | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.806 |
BDI_2337 | hisG | BDI_2337 | BDI_0966 | L-threonine-O-3-phosphate decarboxylase, putative. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. | 0.762 |
BDI_2337 | hisH | BDI_2337 | BDI_2016 | L-threonine-O-3-phosphate decarboxylase, putative. | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.809 |