STRINGSTRING
Amir_1571 Amir_1571 Amir_1579 Amir_1579 ku ku lig lig Amir_1572 Amir_1572 Amir_1538 Amir_1538 Amir_2257 Amir_2257 Amir_0703 Amir_0703 Amir_1570 Amir_1570 Amir_4790 Amir_4790 Amir_2883 Amir_2883
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Amir_1571TIGRFAM: DNA polymerase LigD, polymerase domain protein; PFAM: DNA primase small subunit; KEGG: afw:Anae109_2830 DNA primase small subunit. (330 aa)    
Predicted Functional Partners:
Amir_1579
PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; KEGG: afw:Anae109_4038 ATP-dependent DNA ligase.
   
 0.990
ku
Ku domain containing protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.921
lig
DNA ligase I, ATP-dependent Dnl1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
   
 0.912
Amir_1572
Hypothetical protein.
       0.639
Amir_1538
PFAM: protein of unknown function DUF72; KEGG: xac:XAC2920 hypothetical protein.
 
    0.602
Amir_2257
PFAM: 5'-3' exonuclease; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; KEGG: rce:RC1_2483 DNA polymerase I, putative.
  
   
 0.525
Amir_0703
KEGG: scl:sce7470 hypothetical protein.
  
     0.503
Amir_1570
PFAM: acyl-CoA dehydrogenase domain protein; Acyl- CoA dehydrogenase type 2 domain; KEGG: gur:Gura_3313 acyl-CoA dehydrogenase domain- containing protein.
       0.501
Amir_4790
KEGG: reh:H16_A1489 DNA topoisomerase IB.
 
     0.481
Amir_2883
TIGRFAM: HhH-GPD family protein; PFAM: HhH-GPD family protein.
  
   
 0.476
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
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