STRINGSTRING
Ndas_3699 Ndas_3699 Ndas_3428 Ndas_3428 Ndas_0170 Ndas_0170 Ndas_3698 Ndas_3698 Ndas_5202 Ndas_5202 Ndas_0161 Ndas_0161 Ndas_3313 Ndas_3313
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ndas_3699Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR003607:IPR006675:IPR006674; KEGG: tfu:Tfu_0550 metal-dependent phosphohydrolase, HD region; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: C1YU36 Uncharacterized domain HDIG-containing protein; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG. (469 aa)    
Predicted Functional Partners:
Ndas_3428
Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: tfu:Tfu_2218 GGDEF; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: C1YQA6 Diguanylate cyclase (GGDEF) domain-containing protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
 0.929
Ndas_0170
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterProIPR000160:IPR000014:IPR001633:IPR001610:IPR 013655; KEGG: tfu:Tfu_0610 diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; GGDEF domain containing protein; PAS fold-3 domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein; SPTR: C1YHV9 PAS domain S-box/diguanylate cyclase (GGDEF) domain-containing protein; TIGRFAM: diguanylate [...]
 
 
 0.902
Ndas_3698
Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR006674; KEGG: tfu:Tfu_0551 putative lipoprotein; PFAM: metal-dependent phosphohydrolase HD sub domain; SPTR: C1YU37 HD-GYP domain-containing protein; PFAM: HD domain.
  
0.888
Ndas_5202
GAF sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR009082:IPR003660:IPR001789:IPR003594:IPR 003661:IPR005467:IPR011006:IPR003018:IPR004358; KEGG: tfu:Tfu_0286 GAF sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase HAMP region domain protein; histidine kinase A domain protein; GAF domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; histidine kinase HAMP region domain protein; GAF domain pro [...]
  
 
 0.876
Ndas_0161
Diguanylate cyclase/phosphodiesterase; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR000160:IPR001633; KEGG: tfu:Tfu_0604 diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; SPTR: C1YHH0 Diguanylate cyclase (GGDEF) domain-containing protein; TIGRFAM: diguanylate cyclase; PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
  
 0.691
Ndas_3313
Putative PAS/PAC sensor protein; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterProIPR013655:IPR003018:IPR010822:IPR000014:IPR 001932; KEGG: tfu:Tfu_2140 PAS/protein phosphatase 2C-like; PFAM: Stage II sporulation E family protein; PAS fold-3 domain protein; GAF domain protein; SMART: protein phosphatase 2C domain protein; GAF domain protein; PAS domain containing protein; SPTR: C1YVD0 PAS domain S-box; TIGRFAM: PAS sensor protein; PFAM: GAF domain; Stage II sporulation protein E (SpoIIE); PAS fold; TIGRFAM: PAS domain S-box.
 
   
 0.477
Your Current Organism:
Nocardiopsis dassonvillei
NCBI taxonomy Id: 446468
Other names: N. dassonvillei subsp. dassonvillei DSM 43111, Nocardiopsis dassonvillei DSM 43111, Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111, Nocardiopsis dassonvillei subsp. dassonvillei str. DSM 43111, Nocardiopsis dassonvillei subsp. dassonvillei strain DSM 43111
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.