node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACZ21756.1 | ACZ21991.1 | Sked_18300 | Sked_20690 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. | 0.961 |
ACZ21756.1 | ACZ21993.1 | Sked_18300 | Sked_20710 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Glutamate synthase (NADH) large subunit; PFAM: Glutamine amidotransferases class-II; Glutamate synthase central domain; GXGXG motif; Conserved region in glutamate synthase. | 0.851 |
ACZ21756.1 | ACZ22503.1 | Sked_18300 | Sked_25990 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family. | 0.975 |
ACZ21756.1 | eno | Sked_18300 | Sked_07850 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.513 |
ACZ21756.1 | mdh | Sked_18300 | Sked_28070 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.958 |
ACZ21756.1 | mqo | Sked_18300 | Sked_13020 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Malate:quinone-oxidoreductase; PFAM: FAD dependent oxidoreductase; TIGRFAM: malate:quinone-oxidoreductase. | 0.936 |
ACZ21756.1 | pckG | Sked_18300 | Sked_06760 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. | 0.973 |
ACZ21756.1 | ppc | Sked_18300 | Sked_30020 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. | 0.972 |
ACZ21756.1 | purU | Sked_18300 | Sked_28050 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). | 0.800 |
ACZ21991.1 | ACZ21756.1 | Sked_20690 | Sked_18300 | PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.961 |
ACZ21991.1 | ACZ21993.1 | Sked_20690 | Sked_20710 | PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. | Glutamate synthase (NADH) large subunit; PFAM: Glutamine amidotransferases class-II; Glutamate synthase central domain; GXGXG motif; Conserved region in glutamate synthase. | 0.938 |
ACZ21991.1 | ACZ22503.1 | Sked_20690 | Sked_25990 | PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. | PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family. | 0.435 |
ACZ21991.1 | eno | Sked_20690 | Sked_07850 | PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.996 |
ACZ21991.1 | mdh | Sked_20690 | Sked_28070 | PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.716 |
ACZ21991.1 | pckG | Sked_20690 | Sked_06760 | PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. | Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. | 0.943 |
ACZ21991.1 | ppc | Sked_20690 | Sked_30020 | PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. | 0.944 |
ACZ21991.1 | tpiA | Sked_20690 | Sked_20010 | PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.938 |
ACZ21993.1 | ACZ21756.1 | Sked_20710 | Sked_18300 | Glutamate synthase (NADH) large subunit; PFAM: Glutamine amidotransferases class-II; Glutamate synthase central domain; GXGXG motif; Conserved region in glutamate synthase. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.851 |
ACZ21993.1 | ACZ21991.1 | Sked_20710 | Sked_20690 | Glutamate synthase (NADH) large subunit; PFAM: Glutamine amidotransferases class-II; Glutamate synthase central domain; GXGXG motif; Conserved region in glutamate synthase. | PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. | 0.938 |
ACZ21993.1 | ACZ22503.1 | Sked_20710 | Sked_25990 | Glutamate synthase (NADH) large subunit; PFAM: Glutamine amidotransferases class-II; Glutamate synthase central domain; GXGXG motif; Conserved region in glutamate synthase. | PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family. | 0.952 |