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argG argG argH argH argF argF carB carB argC argC argB argB purA purA carA carA aatA aatA argD argD nadB nadB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
argGArgininosuccinate synthase (Citrulline--aspartate ligase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (402 aa)    
Predicted Functional Partners:
argH
Argininosuccinate lyase (Arginosuccinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.999
argF
Ornithine carbamoyltransferase (OTCase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.997
carB
Carbamoyl-phosphate synthase large chain (Carbamoyl-phosphate synthetase ammonia chain); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarB family.
 
 
 0.993
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
 
  
 0.972
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
 
  
 0.968
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.933
carA
Carbamoyl-phosphate synthase, small chain (Carbamoyl-phosphate synthetase glutamine chain); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarA family.
  
 
 0.924
aatA
Aspartate aminotransferase A (Transaminase A; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.921
argD
Acetylornithine aminotransferase (ACOAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.916
nadB
L-aspartate oxidase (LASPO; Catalyzes the oxidation of L-aspartate to iminoaspartate.
     
 0.913
Your Current Organism:
Leptospira biflexa
NCBI taxonomy Id: 456481
Other names: L. biflexa serovar Patoc strain 'Patoc 1 (Paris)', Leptospira biflexa serovar Patoc str. ATCC 23582, Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)', Leptospira biflexa serovar Patoc strain Patoc 1
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