node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SGO_0747 | SGO_1635 | SGO_0747 | SGO_1635 | Putative methionine synthase. | L-cysteine desulfhydrase; Identified by match to protein family HMM PF00155. | 0.901 |
SGO_0747 | SGO_1636 | SGO_0747 | SGO_1636 | Putative methionine synthase. | Cystathionine gamma-synthase; Identified by match to protein family HMM PF00202; match to protein family HMM PF01053. | 0.952 |
SGO_0747 | cysD | SGO_0747 | SGO_1334 | Putative methionine synthase. | O-acetylhomoserine (thiol)-lyase; Identified by match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM PF01212; match to protein family HMM TIGR01326. | 0.919 |
SGO_0747 | cysK | SGO_0747 | SGO_0606 | Putative methionine synthase. | Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.825 |
SGO_0747 | hom | SGO_0747 | SGO_0801 | Putative methionine synthase. | Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447. | 0.846 |
SGO_0747 | ilvA | SGO_0747 | SGO_0529 | Putative methionine synthase. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.826 |
SGO_0747 | luxS | SGO_0747 | SGO_0592 | Putative methionine synthase. | Autoinducer-2 production protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.940 |
SGO_0747 | metE | SGO_0747 | SGO_0310 | Putative methionine synthase. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.932 |
SGO_1466 | SGO_1636 | SGO_1466 | SGO_1636 | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | Cystathionine gamma-synthase; Identified by match to protein family HMM PF00202; match to protein family HMM PF01053. | 0.451 |
SGO_1466 | cysK | SGO_1466 | SGO_0606 | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.416 |
SGO_1466 | luxS | SGO_1466 | SGO_0592 | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | Autoinducer-2 production protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.979 |
SGO_1635 | SGO_0747 | SGO_1635 | SGO_0747 | L-cysteine desulfhydrase; Identified by match to protein family HMM PF00155. | Putative methionine synthase. | 0.901 |
SGO_1635 | SGO_1636 | SGO_1635 | SGO_1636 | L-cysteine desulfhydrase; Identified by match to protein family HMM PF00155. | Cystathionine gamma-synthase; Identified by match to protein family HMM PF00202; match to protein family HMM PF01053. | 0.991 |
SGO_1635 | cysD | SGO_1635 | SGO_1334 | L-cysteine desulfhydrase; Identified by match to protein family HMM PF00155. | O-acetylhomoserine (thiol)-lyase; Identified by match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM PF01212; match to protein family HMM TIGR01326. | 0.928 |
SGO_1635 | cysK | SGO_1635 | SGO_0606 | L-cysteine desulfhydrase; Identified by match to protein family HMM PF00155. | Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.926 |
SGO_1635 | hom | SGO_1635 | SGO_0801 | L-cysteine desulfhydrase; Identified by match to protein family HMM PF00155. | Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447. | 0.813 |
SGO_1635 | ilvA | SGO_1635 | SGO_0529 | L-cysteine desulfhydrase; Identified by match to protein family HMM PF00155. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.811 |
SGO_1635 | luxS | SGO_1635 | SGO_0592 | L-cysteine desulfhydrase; Identified by match to protein family HMM PF00155. | Autoinducer-2 production protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.900 |
SGO_1635 | metE | SGO_1635 | SGO_0310 | L-cysteine desulfhydrase; Identified by match to protein family HMM PF00155. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.901 |
SGO_1636 | SGO_0747 | SGO_1636 | SGO_0747 | Cystathionine gamma-synthase; Identified by match to protein family HMM PF00202; match to protein family HMM PF01053. | Putative methionine synthase. | 0.952 |