STRINGSTRING
hsa hsa asp3 asp3 asp1 asp1 asp2 asp2 gtfB gtfB nss nss gtaA gtaA sspA sspA sspB sspB secY2 secY2 fbpA fbpA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
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Coexpression
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[Homology]
Score
hsaStreptococcal hemagglutinin; Identified by similarity to GB:BAA97453.1; match to protein family HMM PF00746; match to protein family HMM TIGR01167. (2178 aa)    
Predicted Functional Partners:
asp3
Accessory secretory protein.
 
   
 0.896
asp1
Accessory secretory protein.
 
   
 0.890
asp2
Accessory sescretory protein.
 
   
 0.866
gtfB
Conserved hypothetical protein; Required for polymorphic O-glycosylation of the serine-rich repeat protein in this bacteria. A stabilizing protein that is part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. The GtfA-GtfB complex adds GlcNAc from UDP-GlcNAc to the substrate protein, attaching the first sugar residue. Stabilizes the glycosylation activity of GtfA. Has no N-acetylglucosaminyl transferase activity on its own.
  
   
 0.828
nss
Nucleotide sugar synthetase-like protein.
  
   
 0.768
gtaA
Glycosyl transferase, group 1 SP1758; Required for polymorphic O-glycosylation of the serine-rich repeat protein in this bacteria. Catalyzes the first step in glycosylation by transferring N-acetylglucosamine from UDP-GlcNAc to serine residues in the substrate protein. Part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon.
  
     0.761
sspA
Identified by match to protein family HMM PF00746; match to protein family HMM PF06696; match to protein family HMM PF08363; match to protein family HMM TIGR01167.
  
   
 0.699
sspB
Identified by match to protein family HMM PF00746; match to protein family HMM PF06696; match to protein family HMM PF08363; match to protein family HMM TIGR01167.
  
   
 0.698
secY2
Preprotein translocase, SecY subunit; Part of the accessory SecA2/SecY2 system specifically required for export of possible cell wall proteins. The central subunit of a protein translocation channel.
 
   
 0.646
fbpA
Identified by match to protein family HMM PF05670; match to protein family HMM PF05833.
      
 0.577
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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