node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SGO_2138 | SGO_2139 | SGO_2138 | SGO_2139 | Septum formation initiator family; Identified by match to protein family HMM PF04977. | S4 RNA-binding domain protein; Identified by match to protein family HMM PF01479. | 0.806 |
SGO_2138 | mfd | SGO_2138 | SGO_2140 | Septum formation initiator family; Identified by match to protein family HMM PF04977. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.644 |
SGO_2138 | pth | SGO_2138 | SGO_2141 | Septum formation initiator family; Identified by match to protein family HMM PF04977. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.646 |
SGO_2138 | tilS | SGO_2138 | SGO_2135 | Septum formation initiator family; Identified by match to protein family HMM PF04977. | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.580 |
SGO_2138 | ychF | SGO_2138 | SGO_2142 | Septum formation initiator family; Identified by match to protein family HMM PF04977. | GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.508 |
SGO_2139 | SGO_2138 | SGO_2139 | SGO_2138 | S4 RNA-binding domain protein; Identified by match to protein family HMM PF01479. | Septum formation initiator family; Identified by match to protein family HMM PF04977. | 0.806 |
SGO_2139 | mfd | SGO_2139 | SGO_2140 | S4 RNA-binding domain protein; Identified by match to protein family HMM PF01479. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.634 |
SGO_2139 | pth | SGO_2139 | SGO_2141 | S4 RNA-binding domain protein; Identified by match to protein family HMM PF01479. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.644 |
SGO_2139 | tilS | SGO_2139 | SGO_2135 | S4 RNA-binding domain protein; Identified by match to protein family HMM PF01479. | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.565 |
SGO_2139 | ychF | SGO_2139 | SGO_2142 | S4 RNA-binding domain protein; Identified by match to protein family HMM PF01479. | GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.508 |
guaA | pheT | SGO_1120 | SGO_0861 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | phenylalanyl-tRNA synthetase, beta subunit; Identified by match to protein family HMM PF01588; match to protein family HMM PF03147; match to protein family HMM PF03483; match to protein family HMM PF03484; match to protein family HMM TIGR00472; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.933 |
guaA | polI | SGO_1120 | SGO_0145 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.742 |
guaA | prfB | SGO_1120 | SGO_1441 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.525 |
guaA | pth | SGO_1120 | SGO_2141 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.689 |
guaA | tilS | SGO_1120 | SGO_2135 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.473 |
guaA | ychF | SGO_1120 | SGO_2142 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.747 |
mfd | SGO_2138 | SGO_2140 | SGO_2138 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Septum formation initiator family; Identified by match to protein family HMM PF04977. | 0.644 |
mfd | SGO_2139 | SGO_2140 | SGO_2139 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | S4 RNA-binding domain protein; Identified by match to protein family HMM PF01479. | 0.634 |
mfd | polI | SGO_2140 | SGO_0145 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.697 |
mfd | prfB | SGO_2140 | SGO_1441 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.662 |