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mshB mshB mshD mshD mshC mshC Tbis_3035 Tbis_3035 Tbis_3394 Tbis_3394 Tbis_1934 Tbis_1934 mshA mshA Tbis_0177 Tbis_0177 Tbis_1935 Tbis_1935 Tbis_2967 Tbis_2967 Tbis_1936 Tbis_1936
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mshB1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D-gluc opyranosidedeacetylase; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. (302 aa)    
Predicted Functional Partners:
mshD
Mycothiol biosynthesis acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
  
   
 0.856
mshC
cysteine/1-D-myo-inosityl 2-amino-2-deoxy-alpha- D-glucopyranoside ligase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
 
 
 0.819
Tbis_3035
Hypothetical protein; KEGG: cti:RALTA_B2259 putative transporter, MFS family.
       0.787
Tbis_3394
Hypothetical protein.
  
    0.762
Tbis_1934
Hypothetical protein.
  
     0.741
mshA
UDP-N-acetylglucosamine; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
  
 0.703
Tbis_0177
Hypothetical protein.
  
     0.675
Tbis_1935
Hypothetical protein.
  
     0.652
Tbis_2967
TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: jan:Jann_0296 glutaredoxin GrxC.
  
   
 0.572
Tbis_1936
PFAM: Phosphoglycerate mutase; KEGG: sfu:Sfum_0238 phosphoglycerate mutase.
 
    0.560
Your Current Organism:
Thermobispora bispora
NCBI taxonomy Id: 469371
Other names: T. bispora DSM 43833, Thermobispora bispora ATCC 19993, Thermobispora bispora DSM 43833, Thermobispora bispora str. DSM 43833, Thermobispora bispora strain DSM 43833
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