node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACV05981.1 | fmt | Ksed_09350 | Ksed_12770 | PFAM: NUDIX domain; Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.918 |
ACV05981.1 | gcvT | Ksed_09350 | Ksed_16310 | PFAM: NUDIX domain; Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.914 |
ACV05981.1 | glyA | Ksed_09350 | Ksed_18300 | PFAM: NUDIX domain; Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.924 |
ACV05981.1 | purN | Ksed_09350 | Ksed_07800 | PFAM: NUDIX domain; Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.923 |
ACV06308.1 | ACV06310.1 | Ksed_12760 | Ksed_12780 | Primosomal protein N' (replication factor Y) - superfamily II helicase; TIGRFAM: primosomal protein N'. | tRNA/rRNA cytosine-C5-methylase; PFAM: NusB family; NOL1/NOP2/sun family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.899 |
ACV06308.1 | ACV06311.1 | Ksed_12760 | Ksed_12790 | Primosomal protein N' (replication factor Y) - superfamily II helicase; TIGRFAM: primosomal protein N'. | Ribulose-5-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.819 |
ACV06308.1 | fmt | Ksed_12760 | Ksed_12770 | Primosomal protein N' (replication factor Y) - superfamily II helicase; TIGRFAM: primosomal protein N'. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.956 |
ACV06308.1 | metK | Ksed_12760 | Ksed_12750 | Primosomal protein N' (replication factor Y) - superfamily II helicase; TIGRFAM: primosomal protein N'. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.815 |
ACV06310.1 | ACV06308.1 | Ksed_12780 | Ksed_12760 | tRNA/rRNA cytosine-C5-methylase; PFAM: NusB family; NOL1/NOP2/sun family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Primosomal protein N' (replication factor Y) - superfamily II helicase; TIGRFAM: primosomal protein N'. | 0.899 |
ACV06310.1 | ACV06311.1 | Ksed_12780 | Ksed_12790 | tRNA/rRNA cytosine-C5-methylase; PFAM: NusB family; NOL1/NOP2/sun family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Ribulose-5-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.944 |
ACV06310.1 | fmt | Ksed_12780 | Ksed_12770 | tRNA/rRNA cytosine-C5-methylase; PFAM: NusB family; NOL1/NOP2/sun family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.977 |
ACV06310.1 | metK | Ksed_12780 | Ksed_12750 | tRNA/rRNA cytosine-C5-methylase; PFAM: NusB family; NOL1/NOP2/sun family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.834 |
ACV06311.1 | ACV06308.1 | Ksed_12790 | Ksed_12760 | Ribulose-5-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | Primosomal protein N' (replication factor Y) - superfamily II helicase; TIGRFAM: primosomal protein N'. | 0.819 |
ACV06311.1 | ACV06310.1 | Ksed_12790 | Ksed_12780 | Ribulose-5-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | tRNA/rRNA cytosine-C5-methylase; PFAM: NusB family; NOL1/NOP2/sun family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.944 |
ACV06311.1 | fmt | Ksed_12790 | Ksed_12770 | Ribulose-5-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.871 |
ACV06311.1 | folD | Ksed_12790 | Ksed_07820 | Ribulose-5-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.499 |
ACV06311.1 | metK | Ksed_12790 | Ksed_12750 | Ribulose-5-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.947 |
fmt | ACV05981.1 | Ksed_12770 | Ksed_09350 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | PFAM: NUDIX domain; Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | 0.918 |
fmt | ACV06308.1 | Ksed_12770 | Ksed_12760 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Primosomal protein N' (replication factor Y) - superfamily II helicase; TIGRFAM: primosomal protein N'. | 0.956 |
fmt | ACV06310.1 | Ksed_12770 | Ksed_12780 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | tRNA/rRNA cytosine-C5-methylase; PFAM: NusB family; NOL1/NOP2/sun family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.977 |