STRINGSTRING
mshA mshA Sros_0957 Sros_0957 Sros_3812 Sros_3812 mca mca gpmA gpmA mshB mshB Sros_9365 Sros_9365 mshD mshD Sros_0954 Sros_0954 Sros_4220 Sros_4220 Sros_5291 Sros_5291
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
mshAGlycosyl transferase, group 1 family protein; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway. (435 aa)    
Predicted Functional Partners:
Sros_0957
Hypothetical protein.
     0.916
Sros_3812
KEGG: sal:Sala_3209 phosphoheptose isomerase.
 
  
 0.859
mca
Conserved hypothetical protein LmbE; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily.
 
  
 0.741
gpmA
Bisphosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
  
 0.719
mshB
Conserved hypothetical protein LmbE; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
  
 0.715
Sros_9365
KEGG: sme:SM_b20249 putative myo-inositol-1- phosphate synthase.
 
 
 0.701
mshD
Hypothetical protein; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
  
   
 0.677
Sros_0954
KEGG: mxa:MXAN_2356 hypothetical protein.
 
    0.635
Sros_4220
KEGG: smd:Smed_1698 LmbE family protein.
 
  
 0.628
Sros_5291
Hypothetical protein.
  
     0.612
Your Current Organism:
Streptosporangium roseum
NCBI taxonomy Id: 479432
Other names: S. roseum DSM 43021, Streptosporangium roseum DSM 43021, Streptosporangium roseum str. DSM 43021, Streptosporangium roseum strain DSM 43021
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