node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEI65910.1 | AEI67554.1 | LILAB_20040 | LILAB_28335 | 5'-nucleotidase family protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases. | Cytidine and deoxycytidylate deaminase zinc-binding domain-containing protein; COG2131 Deoxycytidylate deaminase. | 0.991 |
AEI65910.1 | AEI68772.1 | LILAB_20040 | LILAB_34455 | 5'-nucleotidase family protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases. | 5`-nucleotidase family protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | 0.935 |
AEI65910.1 | AEI69078.1 | LILAB_20040 | LILAB_36005 | 5'-nucleotidase family protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.992 |
AEI65910.1 | AEI69082.1 | LILAB_20040 | LILAB_36025 | 5'-nucleotidase family protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases. | COG0213 Thymidine phosphorylase. | 0.992 |
AEI65910.1 | deoD | LILAB_20040 | LILAB_19225 | 5'-nucleotidase family protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases. | COG0813 Purine-nucleoside phosphorylase. | 0.996 |
AEI65910.1 | tdk | LILAB_20040 | LILAB_33315 | 5'-nucleotidase family protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases. | COG1435 Thymidine kinase. | 0.923 |
AEI65910.1 | thyA | LILAB_20040 | LILAB_16555 | 5'-nucleotidase family protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.991 |
AEI65910.1 | tmk | LILAB_20040 | LILAB_20590 | 5'-nucleotidase family protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.916 |
AEI65910.1 | tmk-2 | LILAB_20040 | LILAB_24840 | 5'-nucleotidase family protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.916 |
AEI67554.1 | AEI65910.1 | LILAB_28335 | LILAB_20040 | Cytidine and deoxycytidylate deaminase zinc-binding domain-containing protein; COG2131 Deoxycytidylate deaminase. | 5'-nucleotidase family protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases. | 0.991 |
AEI67554.1 | AEI68772.1 | LILAB_28335 | LILAB_34455 | Cytidine and deoxycytidylate deaminase zinc-binding domain-containing protein; COG2131 Deoxycytidylate deaminase. | 5`-nucleotidase family protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | 0.911 |
AEI67554.1 | AEI69078.1 | LILAB_28335 | LILAB_36005 | Cytidine and deoxycytidylate deaminase zinc-binding domain-containing protein; COG2131 Deoxycytidylate deaminase. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.400 |
AEI67554.1 | dut | LILAB_28335 | LILAB_18155 | Cytidine and deoxycytidylate deaminase zinc-binding domain-containing protein; COG2131 Deoxycytidylate deaminase. | dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.995 |
AEI67554.1 | tdk | LILAB_28335 | LILAB_33315 | Cytidine and deoxycytidylate deaminase zinc-binding domain-containing protein; COG2131 Deoxycytidylate deaminase. | COG1435 Thymidine kinase. | 0.994 |
AEI67554.1 | thyA | LILAB_28335 | LILAB_16555 | Cytidine and deoxycytidylate deaminase zinc-binding domain-containing protein; COG2131 Deoxycytidylate deaminase. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.994 |
AEI67554.1 | tmk | LILAB_28335 | LILAB_20590 | Cytidine and deoxycytidylate deaminase zinc-binding domain-containing protein; COG2131 Deoxycytidylate deaminase. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.993 |
AEI67554.1 | tmk-2 | LILAB_28335 | LILAB_24840 | Cytidine and deoxycytidylate deaminase zinc-binding domain-containing protein; COG2131 Deoxycytidylate deaminase. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.993 |
AEI68772.1 | AEI65910.1 | LILAB_34455 | LILAB_20040 | 5`-nucleotidase family protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | 5'-nucleotidase family protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases. | 0.935 |
AEI68772.1 | AEI67554.1 | LILAB_34455 | LILAB_28335 | 5`-nucleotidase family protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | Cytidine and deoxycytidylate deaminase zinc-binding domain-containing protein; COG2131 Deoxycytidylate deaminase. | 0.911 |
AEI68772.1 | AEI69078.1 | LILAB_34455 | LILAB_36005 | 5`-nucleotidase family protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.914 |