node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ECM30 | MAK32 | YLR436C | YCR019W | Protein of unknown function; may play a role in cell wall biosynthesis, mutants have abormal relative levels of mannose and glucose and have Gap1p sorting and transport defects; (GFP)-fusion protein localizes to the cytoplasm. | Protein necessary for stability of L-A dsRNA-containing particles. | 0.630 |
ECM30 | YCR007C | YLR436C | YCR007C | Protein of unknown function; may play a role in cell wall biosynthesis, mutants have abormal relative levels of mannose and glucose and have Gap1p sorting and transport defects; (GFP)-fusion protein localizes to the cytoplasm. | DUP240 protein YCR007C; Putative integral membrane protein; member of DUP240 gene family; SWAT-GFP and mCherry fusion proteins localize to the cell periphery and vacuole; YCR007C is not an essential gene. | 0.600 |
ECM30 | YCR022C | YLR436C | YCR022C | Protein of unknown function; may play a role in cell wall biosynthesis, mutants have abormal relative levels of mannose and glucose and have Gap1p sorting and transport defects; (GFP)-fusion protein localizes to the cytoplasm. | Uncharacterized protein YCR022C; Putative protein of unknown function; conserved among S. cerevisiae strains; YCR022C is not an essential gene. | 0.791 |
ECM30 | YCR051W | YLR436C | YCR051W | Protein of unknown function; may play a role in cell wall biosynthesis, mutants have abormal relative levels of mannose and glucose and have Gap1p sorting and transport defects; (GFP)-fusion protein localizes to the cytoplasm. | Ankyrin repeat-containing protein YCR051W; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; contains ankyrin (Ank) repeats; YCR051W is not an essential gene. | 0.609 |
ECM30 | YGR176W | YLR436C | YGR176W | Protein of unknown function; may play a role in cell wall biosynthesis, mutants have abormal relative levels of mannose and glucose and have Gap1p sorting and transport defects; (GFP)-fusion protein localizes to the cytoplasm. | Putative uncharacterized protein YGR176W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | 0.700 |
ECM30 | YIR020C | YLR436C | YIR020C | Protein of unknown function; may play a role in cell wall biosynthesis, mutants have abormal relative levels of mannose and glucose and have Gap1p sorting and transport defects; (GFP)-fusion protein localizes to the cytoplasm. | Uncharacterized protein YIR020C; Protein of unknown function; mRNA identified as translated by ribosome profiling data; SWAT-GFP fusion protein localizes to the endoplasmic reticulum. | 0.791 |
ENV10 | YCR007C | YLR065C | YCR007C | Protein involved in SRP-independent targeting of substrates to the ER; component of an alternative ER targeting pathway that has partial functional redundancy with the GET pathway; preference for substrates with downstream transmembrane domains; interacts with Snd1p, Pho88p/Snd3p, and Sec61p-translocon subunits; can compensate for loss of SRP; role in the late endosome-vacuole interface; putative role in secretory protein quality control; Belongs to the TMEM208 family. | DUP240 protein YCR007C; Putative integral membrane protein; member of DUP240 gene family; SWAT-GFP and mCherry fusion proteins localize to the cell periphery and vacuole; YCR007C is not an essential gene. | 0.538 |
HHY1 | SRD1 | YEL059W | YCR018C | Hypersensitivity to hygromycin-B protein 1; Dubious open reading frame unlikely to encode a functional protein; mutant is hypersensitive to hygromycin B indicative of defects in vacuolar trafficking. | Pre-rRNA-processing protein SRD1; Protein involved in the processing of pre-rRNA to mature rRNA; contains a C2/C2 zinc finger motif; srd1 mutation suppresses defects caused by the rrp1-1 mutation. | 0.489 |
HHY1 | YCR007C | YEL059W | YCR007C | Hypersensitivity to hygromycin-B protein 1; Dubious open reading frame unlikely to encode a functional protein; mutant is hypersensitive to hygromycin B indicative of defects in vacuolar trafficking. | DUP240 protein YCR007C; Putative integral membrane protein; member of DUP240 gene family; SWAT-GFP and mCherry fusion proteins localize to the cell periphery and vacuole; YCR007C is not an essential gene. | 0.567 |
HHY1 | ZRG8 | YEL059W | YER033C | Hypersensitivity to hygromycin-B protein 1; Dubious open reading frame unlikely to encode a functional protein; mutant is hypersensitive to hygromycin B indicative of defects in vacuolar trafficking. | Zinc-regulated protein 8; Protein of unknown function; authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; GFP-fusion protein is localized to the cytoplasm; transcription induced under conditions of zinc deficiency. | 0.604 |
MAK32 | ECM30 | YCR019W | YLR436C | Protein necessary for stability of L-A dsRNA-containing particles. | Protein of unknown function; may play a role in cell wall biosynthesis, mutants have abormal relative levels of mannose and glucose and have Gap1p sorting and transport defects; (GFP)-fusion protein localizes to the cytoplasm. | 0.630 |
MAK32 | YCR007C | YCR019W | YCR007C | Protein necessary for stability of L-A dsRNA-containing particles. | DUP240 protein YCR007C; Putative integral membrane protein; member of DUP240 gene family; SWAT-GFP and mCherry fusion proteins localize to the cell periphery and vacuole; YCR007C is not an essential gene. | 0.619 |
MAK32 | YCR022C | YCR019W | YCR022C | Protein necessary for stability of L-A dsRNA-containing particles. | Uncharacterized protein YCR022C; Putative protein of unknown function; conserved among S. cerevisiae strains; YCR022C is not an essential gene. | 0.800 |
MAK32 | YCR051W | YCR019W | YCR051W | Protein necessary for stability of L-A dsRNA-containing particles. | Ankyrin repeat-containing protein YCR051W; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; contains ankyrin (Ank) repeats; YCR051W is not an essential gene. | 0.634 |
MAK32 | YGR176W | YCR019W | YGR176W | Protein necessary for stability of L-A dsRNA-containing particles. | Putative uncharacterized protein YGR176W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | 0.755 |
MAK32 | YIR020C | YCR019W | YIR020C | Protein necessary for stability of L-A dsRNA-containing particles. | Uncharacterized protein YIR020C; Protein of unknown function; mRNA identified as translated by ribosome profiling data; SWAT-GFP fusion protein localizes to the endoplasmic reticulum. | 0.795 |
SRD1 | HHY1 | YCR018C | YEL059W | Pre-rRNA-processing protein SRD1; Protein involved in the processing of pre-rRNA to mature rRNA; contains a C2/C2 zinc finger motif; srd1 mutation suppresses defects caused by the rrp1-1 mutation. | Hypersensitivity to hygromycin-B protein 1; Dubious open reading frame unlikely to encode a functional protein; mutant is hypersensitive to hygromycin B indicative of defects in vacuolar trafficking. | 0.489 |
SRD1 | YCR007C | YCR018C | YCR007C | Pre-rRNA-processing protein SRD1; Protein involved in the processing of pre-rRNA to mature rRNA; contains a C2/C2 zinc finger motif; srd1 mutation suppresses defects caused by the rrp1-1 mutation. | DUP240 protein YCR007C; Putative integral membrane protein; member of DUP240 gene family; SWAT-GFP and mCherry fusion proteins localize to the cell periphery and vacuole; YCR007C is not an essential gene. | 0.513 |
SRD1 | ZRG8 | YCR018C | YER033C | Pre-rRNA-processing protein SRD1; Protein involved in the processing of pre-rRNA to mature rRNA; contains a C2/C2 zinc finger motif; srd1 mutation suppresses defects caused by the rrp1-1 mutation. | Zinc-regulated protein 8; Protein of unknown function; authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; GFP-fusion protein is localized to the cytoplasm; transcription induced under conditions of zinc deficiency. | 0.537 |
YCR007C | ECM30 | YCR007C | YLR436C | DUP240 protein YCR007C; Putative integral membrane protein; member of DUP240 gene family; SWAT-GFP and mCherry fusion proteins localize to the cell periphery and vacuole; YCR007C is not an essential gene. | Protein of unknown function; may play a role in cell wall biosynthesis, mutants have abormal relative levels of mannose and glucose and have Gap1p sorting and transport defects; (GFP)-fusion protein localizes to the cytoplasm. | 0.600 |