Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CTO1 | GTR2 | YCR015C | YGR163W | Protein required for cold tolerance; involved in phosphate uptake; YCR015C is not an essential gene. | GTP-binding protein GTR2; Subunit of a TORC1-stimulating GTPase complex; subunit of the Gtr1-Gtr2 GTPase complex that stimulates TORC1 in response to amino acid stimulation; stimulates the GTPase activity of Gtr1p; negatively regulates the Ran/Tc4 GTPase cycle; activates transcription; tethered to the vacuolar membrane as part of the EGO complex (EGOC); required for sorting of Gap1p; activated by the the Lst4p-Lst7p GAP complex; localizes to cytoplasm and to chromatin; homolog of human RagC and. | 0.733 |
| CTO1 | HEM4 | YCR015C | YOR278W | Protein required for cold tolerance; involved in phosphate uptake; YCR015C is not an essential gene. | Uroporphyrinogen III synthase; catalyzes the conversion of hydroxymethylbilane to uroporphyrinogen III, the fourth step in heme biosynthesis; deficiency in the human homolog can result in the disease congenital erythropoietic porphyria. | 0.556 |
| CTO1 | NAB3 | YCR015C | YPL190C | Protein required for cold tolerance; involved in phosphate uptake; YCR015C is not an essential gene. | RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p); complex interacts with exosome to mediate 3'-end formation of some mRNAs, snRNAs, snoRNAs, and CUTs; required for termination of non-poly(A) transcripts and efficient splicing; Nrd1-Nab3 pathway appears to have a role in rapid suppression of some genes when cells are shifted to poor growth conditions, indicating role for Nrd1-Nab3 in regulating cellular response to nutrient availability. | 0.555 |
| CTO1 | PET18 | YCR015C | YCR020C | Protein required for cold tolerance; involved in phosphate uptake; YCR015C is not an essential gene. | Protein of unknown function; has weak similarity to proteins involved in thiamin metabolism; expression is induced in the absence of thiamin. | 0.815 |
| CTO1 | THI4 | YCR015C | YGR144W | Protein required for cold tolerance; involved in phosphate uptake; YCR015C is not an essential gene. | Thiazole synthase; abundant protein involved in the formation of the thiazole moiety of thiamine during thiamine biosynthesis; acts more as a co-substrate rather than an enzyme by providing the sulphur source for thiazole formation; undergoes a single turnover only; required for mitochondrial genome stability in response to DNA damaging agents; Belongs to the THI4 family. | 0.590 |
| CTO1 | TRS31 | YCR015C | YDR472W | Protein required for cold tolerance; involved in phosphate uptake; YCR015C is not an essential gene. | Core component of transport protein particle (TRAPP) complexes I-III; TRAPP complexes are related multimeric guanine nucleotide-exchange factor for the GTPase Ypt1p, regulating ER-Golgi traffic (TRAPPI), intra-Golgi traffic (TRAPPII), endosome-Golgi traffic (TRAPPII and III) and autophagy (TRAPPIII). | 0.617 |
| CTO1 | YCL001W-B | YCR015C | YCL001W-B | Protein required for cold tolerance; involved in phosphate uptake; YCR015C is not an essential gene. | Putative protein of unknown function; present in a region duplicated between chromosomes XIV and III; YCL001W-B has a paralog, DOM34, that arose from the whole genome duplication; Belongs to the eukaryotic release factor 1 family. Pelota subfamily. Highly divergent. | 0.693 |
| CTO1 | YCL049C | YCR015C | YCL049C | Protein required for cold tolerance; involved in phosphate uptake; YCR015C is not an essential gene. | Uncharacterized protein YCL049C; Protein of unknown function; localizes to membrane fraction; YCL049C is not an essential gene. | 0.602 |
| CTO1 | YCL068C | YCR015C | YCL068C | Protein required for cold tolerance; involved in phosphate uptake; YCR015C is not an essential gene. | Putative protein of unknown function. | 0.759 |
| CTO1 | YDR042C | YCR015C | YDR042C | Protein required for cold tolerance; involved in phosphate uptake; YCR015C is not an essential gene. | Uncharacterized protein YDR042C; Putative protein of unknown function; expression is increased in ssu72-ts69 mutant. | 0.602 |
| GTR2 | CTO1 | YGR163W | YCR015C | GTP-binding protein GTR2; Subunit of a TORC1-stimulating GTPase complex; subunit of the Gtr1-Gtr2 GTPase complex that stimulates TORC1 in response to amino acid stimulation; stimulates the GTPase activity of Gtr1p; negatively regulates the Ran/Tc4 GTPase cycle; activates transcription; tethered to the vacuolar membrane as part of the EGO complex (EGOC); required for sorting of Gap1p; activated by the the Lst4p-Lst7p GAP complex; localizes to cytoplasm and to chromatin; homolog of human RagC and. | Protein required for cold tolerance; involved in phosphate uptake; YCR015C is not an essential gene. | 0.733 |
| HEM4 | CTO1 | YOR278W | YCR015C | Uroporphyrinogen III synthase; catalyzes the conversion of hydroxymethylbilane to uroporphyrinogen III, the fourth step in heme biosynthesis; deficiency in the human homolog can result in the disease congenital erythropoietic porphyria. | Protein required for cold tolerance; involved in phosphate uptake; YCR015C is not an essential gene. | 0.556 |
| HEM4 | TRS31 | YOR278W | YDR472W | Uroporphyrinogen III synthase; catalyzes the conversion of hydroxymethylbilane to uroporphyrinogen III, the fourth step in heme biosynthesis; deficiency in the human homolog can result in the disease congenital erythropoietic porphyria. | Core component of transport protein particle (TRAPP) complexes I-III; TRAPP complexes are related multimeric guanine nucleotide-exchange factor for the GTPase Ypt1p, regulating ER-Golgi traffic (TRAPPI), intra-Golgi traffic (TRAPPII), endosome-Golgi traffic (TRAPPII and III) and autophagy (TRAPPIII). | 0.575 |
| HEM4 | YDR042C | YOR278W | YDR042C | Uroporphyrinogen III synthase; catalyzes the conversion of hydroxymethylbilane to uroporphyrinogen III, the fourth step in heme biosynthesis; deficiency in the human homolog can result in the disease congenital erythropoietic porphyria. | Uncharacterized protein YDR042C; Putative protein of unknown function; expression is increased in ssu72-ts69 mutant. | 0.421 |
| NAB3 | CTO1 | YPL190C | YCR015C | RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p); complex interacts with exosome to mediate 3'-end formation of some mRNAs, snRNAs, snoRNAs, and CUTs; required for termination of non-poly(A) transcripts and efficient splicing; Nrd1-Nab3 pathway appears to have a role in rapid suppression of some genes when cells are shifted to poor growth conditions, indicating role for Nrd1-Nab3 in regulating cellular response to nutrient availability. | Protein required for cold tolerance; involved in phosphate uptake; YCR015C is not an essential gene. | 0.555 |
| NAB3 | TRS31 | YPL190C | YDR472W | RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p); complex interacts with exosome to mediate 3'-end formation of some mRNAs, snRNAs, snoRNAs, and CUTs; required for termination of non-poly(A) transcripts and efficient splicing; Nrd1-Nab3 pathway appears to have a role in rapid suppression of some genes when cells are shifted to poor growth conditions, indicating role for Nrd1-Nab3 in regulating cellular response to nutrient availability. | Core component of transport protein particle (TRAPP) complexes I-III; TRAPP complexes are related multimeric guanine nucleotide-exchange factor for the GTPase Ypt1p, regulating ER-Golgi traffic (TRAPPI), intra-Golgi traffic (TRAPPII), endosome-Golgi traffic (TRAPPII and III) and autophagy (TRAPPIII). | 0.608 |
| PET18 | CTO1 | YCR020C | YCR015C | Protein of unknown function; has weak similarity to proteins involved in thiamin metabolism; expression is induced in the absence of thiamin. | Protein required for cold tolerance; involved in phosphate uptake; YCR015C is not an essential gene. | 0.815 |
| PET18 | THI4 | YCR020C | YGR144W | Protein of unknown function; has weak similarity to proteins involved in thiamin metabolism; expression is induced in the absence of thiamin. | Thiazole synthase; abundant protein involved in the formation of the thiazole moiety of thiamine during thiamine biosynthesis; acts more as a co-substrate rather than an enzyme by providing the sulphur source for thiazole formation; undergoes a single turnover only; required for mitochondrial genome stability in response to DNA damaging agents; Belongs to the THI4 family. | 0.723 |
| THI4 | CTO1 | YGR144W | YCR015C | Thiazole synthase; abundant protein involved in the formation of the thiazole moiety of thiamine during thiamine biosynthesis; acts more as a co-substrate rather than an enzyme by providing the sulphur source for thiazole formation; undergoes a single turnover only; required for mitochondrial genome stability in response to DNA damaging agents; Belongs to the THI4 family. | Protein required for cold tolerance; involved in phosphate uptake; YCR015C is not an essential gene. | 0.590 |
| THI4 | PET18 | YGR144W | YCR020C | Thiazole synthase; abundant protein involved in the formation of the thiazole moiety of thiamine during thiamine biosynthesis; acts more as a co-substrate rather than an enzyme by providing the sulphur source for thiazole formation; undergoes a single turnover only; required for mitochondrial genome stability in response to DNA damaging agents; Belongs to the THI4 family. | Protein of unknown function; has weak similarity to proteins involved in thiamin metabolism; expression is induced in the absence of thiamin. | 0.723 |
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