STRINGSTRING
rof rof yaeP yaeP rho rho yahJ yahJ arfB arfB yjjW yjjW yahD yahD yahG yahG yjjI yjjI yaeQ yaeQ nlpE nlpE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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rofModulator of Rho-dependent transcription termination; Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination. (84 aa)    
Predicted Functional Partners:
yaeP
UPF0253 family protein; Belongs to the UPF0253 family.
  
  
 0.931
rho
Transcription termination factor; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. RNA-dependent NTPase which utilizes all four ribonucleoside triphosphates as substrates.
    
 
 0.803
yahJ
Putative metallo-dependent hydrolase domain deaminase; Putative deaminase; Protein involved in amine catabolic process.
      
 0.711
arfB
Alternative stalled-ribosome rescue factor B; Rescues stalled ribosomes. Can hydrolyze peptidyl-tRNA on ribosomes stalled by both non-stop mRNAs and mRNAs that contain rare codon clusters or ribosomes stalled in the middle of mRNA. First identified as a complementary ribosome rescue system when the stalled ribosome cannot be rescued by the SsrA(tmRNA)- SmpB quality control system or the alternative ribosome-rescue factor A (arfA).
  
    0.549
yjjW
Putative activating enzyme; Protein involved in anaerobic respiration and protein modification process; Belongs to the organic radical-activating enzymes family.
      
 0.547
yahD
Ankyrin repeat protein; Putative transcription factor.
   
  
 0.534
yahG
DUF1116 family protein.
      
 0.528
yjjI
DUF3029 family protein, putative glycine radical enzyme.
      
 0.519
yaeQ
PDDEXK superfamily protein.
  
    0.516
nlpE
Lipoprotein involved with copper homeostasis and adhesion; Involved in copper homeostasis, could be involved in both copper efflux and the delivery of copper to copper-dependent enzymes. Required for efficient binding of stationary phase cells to hydrophobic surfaces, part of the process of biofilm formation. Functions during envelope stress responses; when overproduced induces degP through the activation of the two-component envelope stress response system CpxA/CpxR. DegP induction seems to require membrane anchoring of this protein. Structural changes and/or interaction of the CXXC m [...]
  
    0.513
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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