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yaiV yaiV ygeG ygeG ygcW ygcW ibsD ibsD narV narV ebgC ebgC torZ torZ arcB arcB barA barA evgS evgS sfmZ sfmZ
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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yaiVPutative transcriptional regulator; Involved in oxidative stress resistance; Belongs to the IprA family. (207 aa)    
Predicted Functional Partners:
ygeG
Uncharacterized protein YgeG; Pseudogene; Belongs to the LcrH/SycD chaperone family.
   
 0.764
ygcW
Putative oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.648
ibsD
Toxic membrane protein.
      
 0.620
narV
Nitrate reductase 2 (NRZ), gamma subunit; This is a second nitrate reductase enzyme which can substitute for the NRA enzyme and allows E.coli to use nitrate as an electron acceptor during anaerobic growth. The gamma chain is a membrane-embedded heme-iron unit resembling cytochrome b, which transfers electrons from quinones to the beta subunit.
  
  
 0.590
ebgC
Evolved beta-D-galactosidase, beta subunit; Required for full activity of the EbgA enzyme. Exact function not known.
   
  
 0.531
torZ
Trimethylamine N-oxide reductase system III, catalytic subunit; Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions. Can also reduce other N- and S-oxide compounds such as 4-methylmorpholine-N- oxide and biotin sulfoxide (BSO), but with a lower catalytic efficiency; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
   
  
 0.513
arcB
Aerobic respiration control sensor protein ArcB; Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His-717 and Asp-576.
  
 
 0.493
barA
Hybrid sensory histidine kinase, in two-component regulatory system with UvrY; Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. Phosphorylates UvrY, probably via a four-step phosphorelay.
  
 
 0.462
evgS
Hybrid sensory histidine kinase in two-component regulatory system with EvgA; Member of the two-component regulatory system EvgS/EvgA. Phosphorylates EvgA via a four-step phosphorelay in response to environmental signals.
   
 
 0.455
sfmZ
Response regulator family protein; Fimbrial Z protein; probable signal transducer; Protein involved in transcription activator activity and transcription.
   
 
 0.439
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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