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ychH ychH cspD cspD glgS glgS yodD yodD uspB uspB ygcG ygcG uspF uspF pth pth bsmA bsmA yobF yobF raiA raiA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ychHDUF2583 family putative inner membrane protein. (92 aa)    
Predicted Functional Partners:
cspD
Inhibitor of DNA replication, cold shock protein homolog; Inhibits DNA replication at both initiation and elongation steps, most probably by binding to the opened, single-stranded regions at replication forks. Plays a regulatory role in chromosomal replication in nutrient-depleted cells.
   
    0.838
glgS
Motility and biofilm regulator; Major determinant of cell surface composition. Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides.
   
    0.721
yodD
Uncharacterized protein.
   
  
 0.671
uspB
Protein involved in response to stress and xenobiotic metabolic process.
   
  
 0.655
ygcG
TPM domain protein, putative phosphatase.
      
 0.644
uspF
Universal stress protein F; Pseudogene, prophage Rac integration site ttcA duplication;Phage or Prophage Related.
   
    0.638
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Involved in lambda inhibition of host protein synthesis. PTH activity may, directly or indirectly, be the target for lambda bar RNA leading to rap cell death.
     
 0.526
bsmA
Bioflm peroxide resistance protein; Involved in protection of biofilms against oxidative stress. Belongs to the BhsA/McbA family.
   
  
 0.510
yobF
DUF2527 family heat-induced protein.
   
  
 0.508
raiA
Cold shock protein associated with 30S ribosomal subunit; During stationary phase prevents 70S dimer formation, probably in order to regulate translation efficiency during transition between the exponential and the stationary phases. During environmental stress such as cold shock or excessive cell density at stationary phase, stabilizes the 70S ribosome against dissociation, inhibits translation elongation and increases translation accuracy. When normal growth conditions are restored, is quickly released from the ribosome. Has been suggested to inhibit translation elongation by blockin [...]
   
  
 0.453
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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