node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aaeR | rcdA | b3243 | b0846 | Transcriptional regulator for aaeXAB operon; Activates transcription of the aaeXAB operon. | Transcriptional regulator of csgD and ybiJI; Regulates the expression of a number of genes involved in biofilm formation and stress response. Target genes include six stress- response transcriptional regulators: csgD, which is a master regulator of biofilm formation, appY, sxy, ycgF, fimB and rcdA itself. This indicates that a large number of genes must be regulated indirectly via these transcriptional regulators. Acts by binding to the upstream region of its target genes. | 0.794 |
aaeR | tufB | b3243 | b3980 | Transcriptional regulator for aaeXAB operon; Activates transcription of the aaeXAB operon. | Translation elongation factor EF-Tu 2; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Plays a stimulatory role in trans-translation, binds tmRNA. (Microbial infection) Upon infection by bacteriophage Qbeta, part of the viral RNA-dependent RNA polymerase complex. With EF-Ts may provide a stabilizing scaffold for the beta (catalytic) subunit. Helps separate the double-stranded RNA of the template and growing RNA during elongation. With the beta subunit helps form the exit tunnel for template RNA. The GTPase acti [...] | 0.893 |
aaeR | ybjH | b3243 | b0843 | Transcriptional regulator for aaeXAB operon; Activates transcription of the aaeXAB operon. | Uncharacterized protein. | 0.726 |
aaeR | ybjI | b3243 | b0844 | Transcriptional regulator for aaeXAB operon; Activates transcription of the aaeXAB operon. | 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase; Catalyzes the dephosphorylation of 5-amino-6-(5-phospho-D- ribitylamino)uracil, and thus could be involved in the riboflavin biosynthesis pathway. Is also able to dephosphorylate flavin mononucleotide (FMN), erythrose 4-phosphate and other phosphoric acid esters. Belongs to the HAD-like hydrolase superfamily. Cof family. | 0.762 |
aaeR | ybjJ | b3243 | b0845 | Transcriptional regulator for aaeXAB operon; Activates transcription of the aaeXAB operon. | Putative drug efflux MFS transporter, inner membrane protein; Putative DEOR-type transcriptional regulator. | 0.740 |
aaeR | yiaU | b3243 | b3585 | Transcriptional regulator for aaeXAB operon; Activates transcription of the aaeXAB operon. | Putative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family. | 0.702 |
aaeR | ynfL | b3243 | b1595 | Transcriptional regulator for aaeXAB operon; Activates transcription of the aaeXAB operon. | Putative transcriptional regulator LYSR-type; Protein involved in regulation of transcription, DNA-dependent; Belongs to the LysR transcriptional regulatory family. | 0.752 |
dmlR | yiaU | b1799 | b3585 | Transcriptional activator of dmlA; Transcriptional regulator required for the aerobic growth on D-malate as the sole carbon source. Induces the expression of dmlA in response to D-malate or L- or meso-tartrate. Negatively regulates its own expression. | Putative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family. | 0.761 |
dmlR | ynfL | b1799 | b1595 | Transcriptional activator of dmlA; Transcriptional regulator required for the aerobic growth on D-malate as the sole carbon source. Induces the expression of dmlA in response to D-malate or L- or meso-tartrate. Negatively regulates its own expression. | Putative transcriptional regulator LYSR-type; Protein involved in regulation of transcription, DNA-dependent; Belongs to the LysR transcriptional regulatory family. | 0.704 |
dsdC | ynfL | b2364 | b1595 | Dsd operon activator; Regulates the expression of the dsdX-dsdA operon. | Putative transcriptional regulator LYSR-type; Protein involved in regulation of transcription, DNA-dependent; Belongs to the LysR transcriptional regulatory family. | 0.704 |
rcdA | aaeR | b0846 | b3243 | Transcriptional regulator of csgD and ybiJI; Regulates the expression of a number of genes involved in biofilm formation and stress response. Target genes include six stress- response transcriptional regulators: csgD, which is a master regulator of biofilm formation, appY, sxy, ycgF, fimB and rcdA itself. This indicates that a large number of genes must be regulated indirectly via these transcriptional regulators. Acts by binding to the upstream region of its target genes. | Transcriptional regulator for aaeXAB operon; Activates transcription of the aaeXAB operon. | 0.794 |
rcdA | ttdR | b0846 | b3060 | Transcriptional regulator of csgD and ybiJI; Regulates the expression of a number of genes involved in biofilm formation and stress response. Target genes include six stress- response transcriptional regulators: csgD, which is a master regulator of biofilm formation, appY, sxy, ycgF, fimB and rcdA itself. This indicates that a large number of genes must be regulated indirectly via these transcriptional regulators. Acts by binding to the upstream region of its target genes. | Transcriptional activator of ttdABT; Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB-ygjE operon. | 0.522 |
rcdA | tufB | b0846 | b3980 | Transcriptional regulator of csgD and ybiJI; Regulates the expression of a number of genes involved in biofilm formation and stress response. Target genes include six stress- response transcriptional regulators: csgD, which is a master regulator of biofilm formation, appY, sxy, ycgF, fimB and rcdA itself. This indicates that a large number of genes must be regulated indirectly via these transcriptional regulators. Acts by binding to the upstream region of its target genes. | Translation elongation factor EF-Tu 2; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Plays a stimulatory role in trans-translation, binds tmRNA. (Microbial infection) Upon infection by bacteriophage Qbeta, part of the viral RNA-dependent RNA polymerase complex. With EF-Ts may provide a stabilizing scaffold for the beta (catalytic) subunit. Helps separate the double-stranded RNA of the template and growing RNA during elongation. With the beta subunit helps form the exit tunnel for template RNA. The GTPase acti [...] | 0.906 |
rcdA | ybjH | b0846 | b0843 | Transcriptional regulator of csgD and ybiJI; Regulates the expression of a number of genes involved in biofilm formation and stress response. Target genes include six stress- response transcriptional regulators: csgD, which is a master regulator of biofilm formation, appY, sxy, ycgF, fimB and rcdA itself. This indicates that a large number of genes must be regulated indirectly via these transcriptional regulators. Acts by binding to the upstream region of its target genes. | Uncharacterized protein. | 0.845 |
rcdA | ybjI | b0846 | b0844 | Transcriptional regulator of csgD and ybiJI; Regulates the expression of a number of genes involved in biofilm formation and stress response. Target genes include six stress- response transcriptional regulators: csgD, which is a master regulator of biofilm formation, appY, sxy, ycgF, fimB and rcdA itself. This indicates that a large number of genes must be regulated indirectly via these transcriptional regulators. Acts by binding to the upstream region of its target genes. | 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase; Catalyzes the dephosphorylation of 5-amino-6-(5-phospho-D- ribitylamino)uracil, and thus could be involved in the riboflavin biosynthesis pathway. Is also able to dephosphorylate flavin mononucleotide (FMN), erythrose 4-phosphate and other phosphoric acid esters. Belongs to the HAD-like hydrolase superfamily. Cof family. | 0.885 |
rcdA | ybjJ | b0846 | b0845 | Transcriptional regulator of csgD and ybiJI; Regulates the expression of a number of genes involved in biofilm formation and stress response. Target genes include six stress- response transcriptional regulators: csgD, which is a master regulator of biofilm formation, appY, sxy, ycgF, fimB and rcdA itself. This indicates that a large number of genes must be regulated indirectly via these transcriptional regulators. Acts by binding to the upstream region of its target genes. | Putative drug efflux MFS transporter, inner membrane protein; Putative DEOR-type transcriptional regulator. | 0.963 |
rcdA | ynfL | b0846 | b1595 | Transcriptional regulator of csgD and ybiJI; Regulates the expression of a number of genes involved in biofilm formation and stress response. Target genes include six stress- response transcriptional regulators: csgD, which is a master regulator of biofilm formation, appY, sxy, ycgF, fimB and rcdA itself. This indicates that a large number of genes must be regulated indirectly via these transcriptional regulators. Acts by binding to the upstream region of its target genes. | Putative transcriptional regulator LYSR-type; Protein involved in regulation of transcription, DNA-dependent; Belongs to the LysR transcriptional regulatory family. | 0.683 |
ttdR | rcdA | b3060 | b0846 | Transcriptional activator of ttdABT; Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB-ygjE operon. | Transcriptional regulator of csgD and ybiJI; Regulates the expression of a number of genes involved in biofilm formation and stress response. Target genes include six stress- response transcriptional regulators: csgD, which is a master regulator of biofilm formation, appY, sxy, ycgF, fimB and rcdA itself. This indicates that a large number of genes must be regulated indirectly via these transcriptional regulators. Acts by binding to the upstream region of its target genes. | 0.522 |
ttdR | ynfL | b3060 | b1595 | Transcriptional activator of ttdABT; Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB-ygjE operon. | Putative transcriptional regulator LYSR-type; Protein involved in regulation of transcription, DNA-dependent; Belongs to the LysR transcriptional regulatory family. | 0.727 |
tufB | aaeR | b3980 | b3243 | Translation elongation factor EF-Tu 2; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Plays a stimulatory role in trans-translation, binds tmRNA. (Microbial infection) Upon infection by bacteriophage Qbeta, part of the viral RNA-dependent RNA polymerase complex. With EF-Ts may provide a stabilizing scaffold for the beta (catalytic) subunit. Helps separate the double-stranded RNA of the template and growing RNA during elongation. With the beta subunit helps form the exit tunnel for template RNA. The GTPase acti [...] | Transcriptional regulator for aaeXAB operon; Activates transcription of the aaeXAB operon. | 0.893 |