node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
emrA | emrB | b2685 | b2686 | Multidrug efflux system; Part of the tripartite efflux system EmrAB-TolC, which confers resistance to antibiotics such as CCCP, FCCP, 2,4-dinitrophenol and nalidixic acid. EmrA is a drug-binding protein that provides a physical link between EmrB and TolC; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Multidrug efflux system protein; Part of the tripartite efflux system EmrAB-TolC, which confers resistance to antibiotics such as CCCP, FCCP, 2,4-dinitrophenol and nalidixic acid. | 0.999 |
emrA | emrD | b2685 | b3673 | Multidrug efflux system; Part of the tripartite efflux system EmrAB-TolC, which confers resistance to antibiotics such as CCCP, FCCP, 2,4-dinitrophenol and nalidixic acid. EmrA is a drug-binding protein that provides a physical link between EmrB and TolC; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Multidrug efflux system protein; Multidrug resistance pump that participates in a low energy shock adaptive response; Belongs to the major facilitator superfamily. | 0.788 |
emrA | emrK | b2685 | b2368 | Multidrug efflux system; Part of the tripartite efflux system EmrAB-TolC, which confers resistance to antibiotics such as CCCP, FCCP, 2,4-dinitrophenol and nalidixic acid. EmrA is a drug-binding protein that provides a physical link between EmrB and TolC; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Multidrug resistance efflux pump membrane fusion protein; Part of the tripartite efflux system EmrYK-TolC, which confers resistance to various drugs. | 0.588 |
emrA | yebQ | b2685 | b1828 | Multidrug efflux system; Part of the tripartite efflux system EmrAB-TolC, which confers resistance to antibiotics such as CCCP, FCCP, 2,4-dinitrophenol and nalidixic acid. EmrA is a drug-binding protein that provides a physical link between EmrB and TolC; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Putative transport protein. | 0.573 |
emrB | emrA | b2686 | b2685 | Multidrug efflux system protein; Part of the tripartite efflux system EmrAB-TolC, which confers resistance to antibiotics such as CCCP, FCCP, 2,4-dinitrophenol and nalidixic acid. | Multidrug efflux system; Part of the tripartite efflux system EmrAB-TolC, which confers resistance to antibiotics such as CCCP, FCCP, 2,4-dinitrophenol and nalidixic acid. EmrA is a drug-binding protein that provides a physical link between EmrB and TolC; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.999 |
emrB | emrD | b2686 | b3673 | Multidrug efflux system protein; Part of the tripartite efflux system EmrAB-TolC, which confers resistance to antibiotics such as CCCP, FCCP, 2,4-dinitrophenol and nalidixic acid. | Multidrug efflux system protein; Multidrug resistance pump that participates in a low energy shock adaptive response; Belongs to the major facilitator superfamily. | 0.846 |
emrB | emrK | b2686 | b2368 | Multidrug efflux system protein; Part of the tripartite efflux system EmrAB-TolC, which confers resistance to antibiotics such as CCCP, FCCP, 2,4-dinitrophenol and nalidixic acid. | Multidrug resistance efflux pump membrane fusion protein; Part of the tripartite efflux system EmrYK-TolC, which confers resistance to various drugs. | 0.966 |
emrB | yebQ | b2686 | b1828 | Multidrug efflux system protein; Part of the tripartite efflux system EmrAB-TolC, which confers resistance to antibiotics such as CCCP, FCCP, 2,4-dinitrophenol and nalidixic acid. | Putative transport protein. | 0.429 |
emrD | emrA | b3673 | b2685 | Multidrug efflux system protein; Multidrug resistance pump that participates in a low energy shock adaptive response; Belongs to the major facilitator superfamily. | Multidrug efflux system; Part of the tripartite efflux system EmrAB-TolC, which confers resistance to antibiotics such as CCCP, FCCP, 2,4-dinitrophenol and nalidixic acid. EmrA is a drug-binding protein that provides a physical link between EmrB and TolC; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.788 |
emrD | emrB | b3673 | b2686 | Multidrug efflux system protein; Multidrug resistance pump that participates in a low energy shock adaptive response; Belongs to the major facilitator superfamily. | Multidrug efflux system protein; Part of the tripartite efflux system EmrAB-TolC, which confers resistance to antibiotics such as CCCP, FCCP, 2,4-dinitrophenol and nalidixic acid. | 0.846 |
emrD | emrK | b3673 | b2368 | Multidrug efflux system protein; Multidrug resistance pump that participates in a low energy shock adaptive response; Belongs to the major facilitator superfamily. | Multidrug resistance efflux pump membrane fusion protein; Part of the tripartite efflux system EmrYK-TolC, which confers resistance to various drugs. | 0.795 |
emrD | yebQ | b3673 | b1828 | Multidrug efflux system protein; Multidrug resistance pump that participates in a low energy shock adaptive response; Belongs to the major facilitator superfamily. | Putative transport protein. | 0.474 |
emrK | emrA | b2368 | b2685 | Multidrug resistance efflux pump membrane fusion protein; Part of the tripartite efflux system EmrYK-TolC, which confers resistance to various drugs. | Multidrug efflux system; Part of the tripartite efflux system EmrAB-TolC, which confers resistance to antibiotics such as CCCP, FCCP, 2,4-dinitrophenol and nalidixic acid. EmrA is a drug-binding protein that provides a physical link between EmrB and TolC; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.588 |
emrK | emrB | b2368 | b2686 | Multidrug resistance efflux pump membrane fusion protein; Part of the tripartite efflux system EmrYK-TolC, which confers resistance to various drugs. | Multidrug efflux system protein; Part of the tripartite efflux system EmrAB-TolC, which confers resistance to antibiotics such as CCCP, FCCP, 2,4-dinitrophenol and nalidixic acid. | 0.966 |
emrK | emrD | b2368 | b3673 | Multidrug resistance efflux pump membrane fusion protein; Part of the tripartite efflux system EmrYK-TolC, which confers resistance to various drugs. | Multidrug efflux system protein; Multidrug resistance pump that participates in a low energy shock adaptive response; Belongs to the major facilitator superfamily. | 0.795 |
emrK | yebQ | b2368 | b1828 | Multidrug resistance efflux pump membrane fusion protein; Part of the tripartite efflux system EmrYK-TolC, which confers resistance to various drugs. | Putative transport protein. | 0.677 |
kdgR | yebQ | b1827 | b1828 | KDG regulon transcriptional repressor; Transcriptional regulator of the kdgK gene for the kdg kinase and the kdgT gene for the kdg permease. | Putative transport protein. | 0.509 |
ldtB | rcnB | b0819 | b2107 | L,D-transpeptidase linking Lpp to murein; Responsible, at least in part, for anchoring of the major outer membrane lipoprotein (Lpp, also known as the Braun lipoprotein) to the peptidoglycan via a meso-diaminopimelyl-L-Lys- bond on the terminal residue of Lpp. Can be oxidized in vivo, its reduction depends preferentially on DsbG, although DsbC is able to partially replace DsbG; Belongs to the YkuD family. | Periplasmic modulator of Ni and Co efflux; Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly; Belongs to the RcnB family. | 0.484 |
ldtB | yebQ | b0819 | b1828 | L,D-transpeptidase linking Lpp to murein; Responsible, at least in part, for anchoring of the major outer membrane lipoprotein (Lpp, also known as the Braun lipoprotein) to the peptidoglycan via a meso-diaminopimelyl-L-Lys- bond on the terminal residue of Lpp. Can be oxidized in vivo, its reduction depends preferentially on DsbG, although DsbC is able to partially replace DsbG; Belongs to the YkuD family. | Putative transport protein. | 0.453 |
nikC | yebQ | b3478 | b1828 | Nickel ABC transporter permease; Involved in a nickel transport system, probably translocates nickel through the bacterial inner membrane. | Putative transport protein. | 0.547 |