STRINGSTRING
zinT zinT znuA znuA ykgM ykgM znuC znuC znuB znuB zupT zupT pliG pliG yodB yodB zntA zntA modA modA nikA nikA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
zinTZinc and cadmium binding protein, periplasmic; May function as a periplasmic zinc chaperone or mediate direct transport of zinc from the periplasm to the cytoplasm under zinc-limited conditions. Binds zinc with high affinity, and can also bind cadmium, mercury or nickel. Preferentially binds Zn(2+) over Cd(2+). Contains one high affinity metal binding site, and can bind additional metal ions at other sites; Belongs to the calycin superfamily. ZinT family. (216 aa)    
Predicted Functional Partners:
znuA
Zinc ABC transporter periplasmic binding protein; Involved in the high-affinity zinc uptake transport system.
 
  
 0.999
ykgM
50S ribosomal protein L31 type B; alternative zinc-limitation L31 protein.
  
  
 0.996
znuC
Zinc ABC transporter ATPase; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
  
  
 0.979
znuB
Zinc ABC transporter permease; Involved in the high-affinity zinc uptake transport system; Belongs to the ABC-3 integral membrane protein family.
  
  
 0.971
zupT
Zinc transporter; Mediates zinc uptake. May also transport other divalent cations such as copper and cadmium ions; Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
      
 0.891
pliG
Periplasmic inhibitor of g-type lysozyme; Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium.
   
  
 0.883
yodB
Cytochrome b561 homolog 1; Protein involved in cytochrome complex assembly.
  
    0.830
zntA
Zinc, cobalt and lead efflux system; Confers resistance to zinc, cadmium and lead. Couples the hydrolysis of ATP with the export of zinc, cadmium or lead, with highest activity when the metals are present as metal-thiolate complexes. Can also bind nickel, copper, cobalt and mercury. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
   
 
 0.578
modA
Molybdate ABC transporter periplasmic binding protein; Part of the ABC transporter complex ModABC involved in the transport of molybdenum into the cell. Binds molybdate with high affinity in vitro and with a similar affinity in vivo. Binds tungstate with high affinity in vitro. Binds unnatural anion perrhenate with high affinity in vitro. Does not bind sulfate, phosphate, arsenate, selenate, chlorate, metavanadate, nitrate, perchlorate, permanganate or carbonate. Belongs to the bacterial solute-binding protein ModA family.
      
 0.562
nikA
Nickel/heme ABC transporter periplasmic binding protein; Involved in a nickel transport system, probably represents the nickel binder.
      
 0.557
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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