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yfeR yfeR yijO yijO yfeH yfeH yhaJ yhaJ yfhH yfhH yihG yihG metR metR xdhB xdhB ydeS ydeS dmlR dmlR paaX paaX
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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yfeRPutative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family. (308 aa)    
Predicted Functional Partners:
yijO
Putative ARAC-type regulatory protein; Protein involved in transcription activator activity and transcription.
  
  
 0.685
yfeH
Putative inorganic ion transporter; Putative cytochrome oxidase; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
  
  
 0.610
yhaJ
LysR family putative transcriptional regulator; Positive regulator, may be partially responsible for expression of neighboring gene dlsT (yhaO) (By similarity).
  
  
 0.555
yfhH
Putative DNA-binding transcriptional regulator.
   
  
 0.533
yihG
Inner membrane protein, inner membrane acyltransferase; Putative endonuclease.
      
 0.528
metR
Methionine biosynthesis regulon transcriptional regulator; Control of the last step in methionine biosynthesis; MetR is a positive activator of the metA, metE and metH genes. MetR is also a negative regulator of its own expression. Binds homocysteine as an inducer; Belongs to the LysR transcriptional regulatory family.
  
     0.512
xdhB
Xanthine dehydrogenase, FAD-binding subunit; Presumed to be a dehydrogenase, but possibly an oxidase. Participates in limited purine salvage (requires aspartate) but does not support aerobic growth on purines as the sole carbon source (purine catabolism).
      
 0.459
ydeS
Putative fimbrial-like protein.
      
 0.457
dmlR
Transcriptional activator of dmlA; Transcriptional regulator required for the aerobic growth on D-malate as the sole carbon source. Induces the expression of dmlA in response to D-malate or L- or meso-tartrate. Negatively regulates its own expression.
  
   
0.430
paaX
Transcriptional repressor of phenylacetic acid degradation paa operon, phenylacetyl-CoA inducer; Negative regulator of the paaZ and paaABCDEFGHIJK catabolic operons. Binds the consensus sequence 5'-WWTRTGATTCGYGWT-3'. Binding of PaaX is specifically inhibited by phenylacetyl-coenzyme A (PA-CoA).
   
  
 0.401
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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