STRINGSTRING
yfiM yfiM pssA pssA hofM hofM pqiC pqiC yfbK yfbK rutE rutE yecR yecR rzoD rzoD yneJ yneJ pka pka ybeD ybeD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
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[Homology]
Score
yfiMPutative lipoprotein. (107 aa)    
Predicted Functional Partners:
pssA
Phosphatidylserine synthase; phospholipid synthesis; Protein involved in phospholipid biosynthetic process.
       0.652
hofM
DNA catabolic putative pilus assembly protein; Required for the use of extracellular DNA as a nutrient.
      
 0.624
pqiC
DUF330 family putative lipoprotein; Component of a transport pathway that contributes to membrane integrity.
      
 0.621
yfbK
Von Willebrand factor domain putative lipoprotein; To Synechocystis PCC 6803 sll0103.
      
 0.544
rutE
Putative malonic semialdehyde reductase; May reduce toxic product malonic semialdehyde to 3- hydroxypropionic acid, which is excreted. RutE is apparently supplemented by YdfG. Required in vivo, but not in vitro in pyrimidine nitrogen degradation; Belongs to the nitroreductase family. HadB/RutE subfamily.
      
 0.543
yecR
Lipoprotein, function unknown.
      
 0.519
rzoD
DLP12 prophage; Component of the spanin complex that disrupts the outer membrane and causes cell lysis during virus exit. The spanin complex conducts the final step in cell lysis by disrupting the outer membrane after holin and endolysin action have permeabilized the inner membrane and degraded the host peptidoglycans (By similarity); Belongs to the lambdalikevirus o-spanin family.
      
 0.505
yneJ
Putative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family.
      
 0.499
pka
Protein lysine acetyltransferase; Catalyzes the acetyl-CoA-dependent acetylation of lysine residues of a large number of target proteins. Acetylates RNase R in exponential phase cells and RNase II. Required for the glucose-dependent acetylation on multiple lysines of alpha, beta and beta' RNAP subunits. Also acetylates acetyl-coenzyme A synthetase (Acs) and the chromosomal replication initiator protein DnaA, and inhibits their activity. Overexpression leads to the acetylation of a large number of additional proteins and inhibits motility.
       0.453
ybeD
UPF0250 family protein.
      
 0.451
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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