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ygcW ygcW ygcU ygcU kduI kduI nuoC nuoC ygcE ygcE yaiV yaiV ydjJ ydjJ ygjR ygjR yggP yggP ygeG ygeG ydgJ ydgJ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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ygcWPutative oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa)    
Predicted Functional Partners:
ygcU
Putative FAD-linked oxidoreductase; Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
   0.897
kduI
Hexuronate isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity). Plays a role in the catabolism of hexuronates under osmotic stress conditions, likely substituting for the regular hexuronate degrading enzyme UxaC whose expression is repressed in these conditions ; Belongs to the KduI family.
   
 0.735
nuoC
NADH:ubiquinone oxidoreductase, fused CD subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.
   
 
 0.718
ygcE
Putative kinase; Belongs to the FGGY kinase family.
 
    0.694
yaiV
Putative transcriptional regulator; Involved in oxidative stress resistance; Belongs to the IprA family.
   
 0.648
ydjJ
Putative oxidoreductase.
 
    
 0.638
ygjR
Putative NAD(P)-dependent dehydrogenase; Belongs to the Gfo/Idh/MocA family.
   
  
 0.607
yggP
Putative Zn-binding dehydrogenase; To K.pneumoniae SorE.
      
 0.600
ygeG
Uncharacterized protein YgeG; Pseudogene; Belongs to the LcrH/SycD chaperone family.
   
 
 0.562
ydgJ
Putative oxidoreductase.
   
  
 0.546
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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