node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
frvR | waaL | b3897 | b3622 | Putative frv operon regulator; Could be involved in the regulation of the transcription of the FRV operon. | O-antigen ligase; Adds the O-antigen on the glucose group of LPS. | 0.774 |
frvR | waaU | b3897 | b3623 | Putative frv operon regulator; Could be involved in the regulation of the transcription of the FRV operon. | Lipopolysaccharide core biosynthesis; Adds the terminal N-acetyl-D-glucosamine group on the glucose(II) group of LPS. | 0.773 |
frvR | ycjN | b3897 | b1310 | Putative frv operon regulator; Could be involved in the regulation of the transcription of the FRV operon. | Putative ABC sugar transporter periplasmic binding protein; Probably part of the binding-protein-dependent transport system YcjNOP; Belongs to the bacterial solute-binding protein 1 family. | 0.673 |
frvR | ycjQ | b3897 | b1313 | Putative frv operon regulator; Could be involved in the regulation of the transcription of the FRV operon. | Putative Zn-dependent NAD(P)-binding oxidoreductase; Catalyzes the NAD(+)-dependent oxidation of the hydroxyl group at C3 of D-gulosides leading to 3-dehydro-D-gulosides. Probably functions in a metabolic pathway that transforms D-gulosides to D- glucosides. Is also able to catalyze the reverse reactions, i.e. the NADH-dependent reduction of the oxo group at C3 of 3-dehydro-D- gulosides leading to D-gulosides. In vitro, can oxidize D-gulose and methyl beta-D-guloside, and reduce methyl alpha-3-dehydro-D-guloside and methyl beta-3-dehydro-D-guloside. However, the actual specific physiol [...] | 0.584 |
frvR | ycjR | b3897 | b1314 | Putative frv operon regulator; Could be involved in the regulation of the transcription of the FRV operon. | Putative TIM alpha/beta barrel enzyme; Catalyzes the epimerization at C4 of 3-dehydro-D-gulosides leading to 3-dehydro-D-glucosides. Probably functions in a metabolic pathway that transforms D-gulosides to D-glucosides. Can use methyl alpha-3-dehydro-D-glucoside and methyl beta-3-dehydro-D-glucoside as substrates in vitro. However, the actual specific physiological substrates for this metabolic pathway are unknown. Cannot act on D- psicose, D-fructose, D-tagatose, D-sorbose, L-xylulose, or L-ribulose. Belongs to the hyi family. | 0.501 |
frvR | ygcE | b3897 | b2776 | Putative frv operon regulator; Could be involved in the regulation of the transcription of the FRV operon. | Putative kinase; Belongs to the FGGY kinase family. | 0.410 |
frvR | yqcE | b3897 | b2775 | Putative frv operon regulator; Could be involved in the regulation of the transcription of the FRV operon. | Putative MFS transporter, inner membrane protein; Putative transport protein. | 0.766 |
uacT | yijD | b2888 | b3964 | Uric acid permease; Proton-dependent high-capacity transporter for uric acid. Shows also a low capacity for transport of xanthine at 37 degrees Celsius but not at 25 degrees Celsius; Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily. | DUF1422 family inner membrane protein. | 0.732 |
uacT | yqcE | b2888 | b2775 | Uric acid permease; Proton-dependent high-capacity transporter for uric acid. Shows also a low capacity for transport of xanthine at 37 degrees Celsius but not at 25 degrees Celsius; Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily. | Putative MFS transporter, inner membrane protein; Putative transport protein. | 0.805 |
waaL | frvR | b3622 | b3897 | O-antigen ligase; Adds the O-antigen on the glucose group of LPS. | Putative frv operon regulator; Could be involved in the regulation of the transcription of the FRV operon. | 0.774 |
waaL | waaU | b3622 | b3623 | O-antigen ligase; Adds the O-antigen on the glucose group of LPS. | Lipopolysaccharide core biosynthesis; Adds the terminal N-acetyl-D-glucosamine group on the glucose(II) group of LPS. | 0.961 |
waaL | ycjN | b3622 | b1310 | O-antigen ligase; Adds the O-antigen on the glucose group of LPS. | Putative ABC sugar transporter periplasmic binding protein; Probably part of the binding-protein-dependent transport system YcjNOP; Belongs to the bacterial solute-binding protein 1 family. | 0.440 |
waaL | yqcE | b3622 | b2775 | O-antigen ligase; Adds the O-antigen on the glucose group of LPS. | Putative MFS transporter, inner membrane protein; Putative transport protein. | 0.704 |
waaU | frvR | b3623 | b3897 | Lipopolysaccharide core biosynthesis; Adds the terminal N-acetyl-D-glucosamine group on the glucose(II) group of LPS. | Putative frv operon regulator; Could be involved in the regulation of the transcription of the FRV operon. | 0.773 |
waaU | waaL | b3623 | b3622 | Lipopolysaccharide core biosynthesis; Adds the terminal N-acetyl-D-glucosamine group on the glucose(II) group of LPS. | O-antigen ligase; Adds the O-antigen on the glucose group of LPS. | 0.961 |
waaU | yqcE | b3623 | b2775 | Lipopolysaccharide core biosynthesis; Adds the terminal N-acetyl-D-glucosamine group on the glucose(II) group of LPS. | Putative MFS transporter, inner membrane protein; Putative transport protein. | 0.673 |
ycjN | frvR | b1310 | b3897 | Putative ABC sugar transporter periplasmic binding protein; Probably part of the binding-protein-dependent transport system YcjNOP; Belongs to the bacterial solute-binding protein 1 family. | Putative frv operon regulator; Could be involved in the regulation of the transcription of the FRV operon. | 0.673 |
ycjN | waaL | b1310 | b3622 | Putative ABC sugar transporter periplasmic binding protein; Probably part of the binding-protein-dependent transport system YcjNOP; Belongs to the bacterial solute-binding protein 1 family. | O-antigen ligase; Adds the O-antigen on the glucose group of LPS. | 0.440 |
ycjN | ycjQ | b1310 | b1313 | Putative ABC sugar transporter periplasmic binding protein; Probably part of the binding-protein-dependent transport system YcjNOP; Belongs to the bacterial solute-binding protein 1 family. | Putative Zn-dependent NAD(P)-binding oxidoreductase; Catalyzes the NAD(+)-dependent oxidation of the hydroxyl group at C3 of D-gulosides leading to 3-dehydro-D-gulosides. Probably functions in a metabolic pathway that transforms D-gulosides to D- glucosides. Is also able to catalyze the reverse reactions, i.e. the NADH-dependent reduction of the oxo group at C3 of 3-dehydro-D- gulosides leading to D-gulosides. In vitro, can oxidize D-gulose and methyl beta-D-guloside, and reduce methyl alpha-3-dehydro-D-guloside and methyl beta-3-dehydro-D-guloside. However, the actual specific physiol [...] | 0.991 |
ycjN | ycjR | b1310 | b1314 | Putative ABC sugar transporter periplasmic binding protein; Probably part of the binding-protein-dependent transport system YcjNOP; Belongs to the bacterial solute-binding protein 1 family. | Putative TIM alpha/beta barrel enzyme; Catalyzes the epimerization at C4 of 3-dehydro-D-gulosides leading to 3-dehydro-D-glucosides. Probably functions in a metabolic pathway that transforms D-gulosides to D-glucosides. Can use methyl alpha-3-dehydro-D-glucoside and methyl beta-3-dehydro-D-glucoside as substrates in vitro. However, the actual specific physiological substrates for this metabolic pathway are unknown. Cannot act on D- psicose, D-fructose, D-tagatose, D-sorbose, L-xylulose, or L-ribulose. Belongs to the hyi family. | 0.991 |